MSRV Retrovirus, phase 2

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Fred1208
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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Thu Dec 04, 2014 6:06 am

Hello,

Here is the information regarding 2a phase :

http://www.geneuro.com/en/news/press_articles.php

The target was only to evaluate the safety of the doses.

I don't have any indication about the fact I was in the placebo arm during the first phase or not.
However, I took the extension of this first phase including placebo, with 100% warranty in this second phase I received the product.

I took only 2 mg/kg which is probably not enough.
As far as I know, roughly 80% of the patients noticed stabilization, even improvements for some cases. All were in progressive stage.

The doses will be higher in the future, roughly 20 mg/kg I think.

Have a good day,

Fred

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Fred1208
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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Mon Jan 26, 2015 4:55 am

Hello

The 2b phase should start this summer.

Some necessary tests have been launched with higher doses (15 and 30 mg/kg).

As far as I know, no problem at this moment.

Have a good day,

Fred

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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Tue Jan 19, 2016 4:13 am

The 18th of december 2015, Geneuro annonced starting of Phase 2b.
Preliminary results at the end of 2017.

You could find a video here : http://www.geneuro.ch/en/news-press

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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Mon Jan 30, 2017 10:35 pm

Hello Everybody.

The 2B phase started in Europe; 260 patients involved, for relapsing MS.
First preliminary results will be given in October.
A 2B phase for progressive MS should start in US very soon.

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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Wed Feb 01, 2017 6:59 am

Bottom of the window, please click for english subtitles


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Fred1208
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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Fri Feb 03, 2017 12:43 pm

Video done in 2014 by Hervé Perron, who was at the origin of this finding.

Same thing, please click on the window bottom to get english subtitles


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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Sun Oct 08, 2017 8:02 am

Geneuro gave preliminary results at 6 months for their 2B study.

At 6 months, there is no difference between their product versus placebo.

BUT

1 there is one year study
2 the study continues, the partner SERVIER still supports them.
3 Geneuro immediately indicates that the action process could be longer. in other terms, it coulde be possible that 6 months could be a too short period to see anything as positive results.
4 Geneuro is going to present at ECTRIMS in paris ( https://www.ectrims-congress.eu/2017.html ) on the 28th of october these 6 months results. It seems they have got data indicating that the action mode is lower ( http://www.geneuro.com/data/news/geneur ... ims-en.pdf ).

Stay tuned.

If there is a confirmation of positive results in Januarry/February 2018, a 2B study will start for progressive forms in US.


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Fred1208
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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Sat Oct 28, 2017 6:23 am


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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Sat Dec 30, 2017 8:52 am

Youtube video with english subtitles
Miguel Payro, financial manager of Geneuro Company:


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lovebug
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Re: MSRV Retrovirus, phase 2

Post by lovebug » Sat Dec 30, 2017 10:48 am

Maybe this is what many of us have been waiting for
Can you imagine ?

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Fred1208
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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Mon Mar 26, 2018 8:34 am

It seems.

A revolution.

Phase2b results :

http://www.geneuro.com/data/news/geneur ... -ms-en.pdf

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Re: MSRV Retrovirus, phase 2

Post by Fred1208 » Wed Jul 25, 2018 11:52 pm


Zyklon
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Re: MSRV Retrovirus, phase 2

Post by Zyklon » Thu Jul 26, 2018 5:29 pm

Worth following trials.
Pain! You made me a, you made me a believer, believer
Pain! You break me down, you build me up, believer, believer
Pain! Oh let the bullets fly, oh let them rain
My life, my love, my drive, it came from... Pain!

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Re: MSRV Retrovirus, phase 2

Post by CureOrBust » Fri Nov 23, 2018 2:10 am

Fred1208 wrote:It seems.

A revolution.

Phase2b results :

http://www.geneuro.com/data/news/geneur ... -ms-en.pdf
But I dont see any results regarding actual EDSS changes? or did I skim read too fast...

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