Myelin peptide transdermal patch

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NHE
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Myelin peptide transdermal patch

Post by NHE » Thu Jul 18, 2013 4:36 pm

Small Study Suggests Possible Benefit for Skin Patch to Reduce Immune Activity in Multiple Sclerosis
http://nationalmssociety.org/news/news- ... x?nid=8012

Polish researchers reported results of a small clinical trial in which a skin patch containing myelin peptides (portions of the substance that insulates nerve fibers and is a target of the immune attack on the brain and spinal cord in MS) were administered to 20 people with relapsing-remitting MS via a skin patch, resulting in significant reductions in disease activity on imaging scans and relapses, compared with 10 people given an inactive placebo patch.1 Over one year, the treatment was found to be safe and well tolerated. Further studies in larger numbers of people are necessary to determine whether this method has potential as a safe and effective treatment approach for people with MS. Agata Walczak, MD, PhD, and Krzysztof Selmaj, MD, PhD (University of Lodz, Poland) and colleagues report their findings in JAMA Neurology.

  1. 66% reduction in gadolinium enhancing lesions, P=0.02
    69% reduction in annual relapse rate, P=0.007

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Slumby
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Re: Myelin peptide transdermal patch

Post by Slumby » Wed Sep 11, 2013 5:05 pm

This is very exciting.
Laura

Secondary progressive
14mg aubagio
Edss = 8
Check out my blog!
Laura5myMSstories.blogspot.com

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CureOrBust
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Re: Myelin peptide transdermal patch

Post by CureOrBust » Thu Sep 12, 2013 4:40 am

You have to be a subscriber to download the PDF, the above link did not work for me. This link gives the abstract etc http://archneur.jamanetwork.com/article ... id=1704351 or this one on pub med http://www.ncbi.nlm.nih.gov/pubmed/23817921

and while searching for another source, I came across this editorial http://www.overcomingmultiplesclerosis. ... ntId=20084

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NHE
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Re: Myelin peptide transdermal patch

Post by NHE » Thu Sep 12, 2013 2:48 pm

CureOrBust wrote:You have to be a subscriber to download the PDF, the above link did not work for me.
It's likely that the NMSS initially had the wrong link on their site and then changed it later.

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