So, I'm concerned about infusion reactions. She said they would pre-medicate me with Benadryl. I'm trying to figure out if I'll be able to drive about 30 miles after the infusion or if I should arrange for someone to accompany me.
Thanks for any input. I'm not usually a wimp about this stuff, but Rituxan scares me.
I had someone drive me for first infusion but it was completely unnecessary. For the next three, I did the 15 minute drive (5.7 miles on a major street w/several traffic lights) myself but had someone nearby on call in case I felt I needed a ride. I could definitely sleep after the infusion but wasn't in any danger of spontaneously falling asleep. I had four weekly infusions including iv and intrathecal injections so it was a bit more hard core than the usual.
Hope that helps and good luck!
“Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis JAMA Neurology, “09/14/2011 Clifford DB et al.
To my knowledge there have been no reported cases of PML in rituxan treated patients with multiple sclerosis; However, there are about 114 total cases in association with rituximab as of 2013
source: “New insights on human polyomavirus JC and pathogenesis of progressive multifocal leukoencephalopathy.”
Clin Dev Immunol. 2013;2013:839719. doi: 10.1155/2013/839719. Epub 2013 Apr 17.; Bellizzi A1, Anzivino E, Rodio DM, Palamara AT, Nencioni L, Pietropaolo V.
However, a lot of these patients received other immunosuppressive drugs as well.