Since we talk about an improvement in the ability to sweat as one of the outcomes of the CCSVI procedure, it is good to establish that a deficiency in sweating is characteristic of MS. This study showed that the sweating threshold in people with MS is a full degree higher than in the healthy controls.Recently, one study has assessed the thermoregulatory center and its impact on multiple sclerosis (3). In this study of a single subject with a history of multiple sclerosis and thermoregulatory dysfunction, temperature thresholds were calculated as the core temperature was slowly warmed to sweating and again as the core temperature was gradually cooled to vasoconstriction and shivering. It was found that the sweating threshold was a full 1°C higher than normal and the vasoconstriction threshold was 2°C below normal, making the calculated sweating-to-vasoconstriction range four times the normal amount. The shivering threshold was also lower than normal (31.8°C), making the vasoconstriction-to-shivering range more than twice the normal amount. Providing such information may sound academic and simplistic; however, this may be an important point to those with multiple sclerosis, altering them to the extent of dysfunction, and to others like caretakers and insurance companies, alerting them to the hazards of increased body temperature and the need for cooling devices.
Jeff just got back from a long bike ride in the heat. No more heat intolerence since his venoplasty...before treatment he had to wear cooling vests and hats during LA summers. No longer. Ahd his body temp is 98.6.The brain is one of the most metabolically active tissues, generating large amounts of heat. Dissipating this heat as well as heat absorbed from the environment has been a major evolutionary hurdle, one that was necessary to overcome for the continued development of the brain and the evolution of humans. Simply put, the brain, like the automobile engine, could not increase in size without the simultaneous development of an adequate cooling system. The brain was constrained and could only develop in parallel to its “cranial radiator” (2). However, for many with multiple sclerosis, the cranial radiator is simply not adequate.
The evolution of emissary veins solved this problem and removed any restraint on brain development. According to this theory, a vascular network in the scalp and face developed with veins draining through emissary veins in the skull joining the meningeal veins and sinuses of the dura mater. From the dura, venous blood drains to veins within the brain, thereby removing heat from the brain. With heat stress, the venous plexus on the face and scalp dilate, promoting heat loss by conduction. In addition, secretomotor pathways activate sweating, further cooling the blood by evaporation. Thus venous blood, the temperature of which is lowered by conduction and evaporation, percolates back to cool the brain (2).
dx dual jugular vein stenosis (CCSVI) 4/09
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At rehab, though, once, somebody told me she didn't have the energy to do enough exercise to break a sweat. Maybe low energy is to avoid overheating because we can't sweat enough to make a difference?
Not a doctor.
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