SPASM AND STIFFNESS AS SPASTICITY
- THEGREEKFROMTHED
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Re: SPASM AND STIFFNESS AS SPASTICITY
Get some greek cafe and some baklava and relax! If jimmylegs helps even just one patient with magnesium defficiency wouldnt that be worth it? Until anyone can figure out what the hell is happening to us than trying something as simple as magnesium and zinc and a few adjustments is not unreasonable. fuck all the "science" Ive been fed the science for 4 years and cant walk. The mris' lumbar punctures, all the bullshit "science" aint doing crap for me. Im on board jimmylegs. Its going to take something fluky to fix us. Not science and rats and mice and gerbles all that bullshit.
No its going to take a guy like Sclafani or Jimmy or maybe even someones ancient chinese secret Mom to fix this disease. Science just keeps bringing harder and harsher and stronger meds.
Science....huh...gasp
τυρί ψωμί και ελιές οι βασιλιάδες των τροφίμων thats science!
Re: SPASM AND STIFFNESS AS SPASTICITY
Re: SPASM AND STIFFNESS AS SPASTICITY
gauchito, spasms may be the result of many medical conditions, however in MS they are is due to the loss of communication between the modulatory upper motor neurons and the0 alpha motor neurons at the lower levels of the spinal cord. This is a phenomenon that is not yet completely understood, but this is the big picture. The wikipedia article, though not scientific, has many references and a good description.
http://en.wikipedia.org/wiki/Spasticity
I don't mean to offend anyone, we are just discussing.
sou
Re: SPASM AND STIFFNESS AS SPASTICITY
I agree, I follow them, too, but I am not really convinced about their efficiency. Much better than useless drugs, though.THEGREEKFROMTHED wrote:SOU, yasoo!
Get some greek cafe and some baklava and relax! If jimmylegs helps even just one patient with magnesium defficiency wouldnt that be worth it? Until anyone can figure out what the hell is happening to us than trying something as simple as magnesium and zinc and a few adjustments is not unreasonable.
I blame scientists, not science.THEGREEKFROMTHED wrote: fuck all the "science" Ive been fed the science for 4 years and cant walk. The mris' lumbar punctures, all the bullshit "science" aint doing crap for me. Im on board jimmylegs. Its going to take something fluky to fix us. Not science and rats and mice and gerbles all that bullshit.
Και θα πάει το ουρικό στο 150! Άσε καλύτερα. Χαχαχαχα!THEGREEKFROMTHED wrote:τυρί ψωμί και ελιές οι βασιλιάδες των τροφίμων thats science!
sou
Re: SPASM AND STIFFNESS AS SPASTICITY
Re: SPASM AND STIFFNESS AS SPASTICITY
as gauchito has mentioned, the wiki info you provided details a couple of reasons for spasticity: multiple sclerosis and cerebral palsy (spastic diplegia being the most common form of CP.. something people tend to get diagnosed with as babies).
both forms have links to magnesium.
Magnesium sulfate and decreased risk of cerebral palsy (2000)
http://www.cpparent.org/cpbooklet.htm#RESEARCH
"Research conducted and supported by the National Institute of Neurological Disorders and Stroke (NINDS) continuously seeks to uncover new clues about cerebral palsy (CP). Investigators from the NINDS and the California Birth Defects Monitoring Program (CBDMP) presented data suggesting that very low birthweight babies have a decreased incidence of CP when their mothers are treated with magnesium sulfate soon before giving birth. The results of this study, which were based on observations of a group of children born in four Northern California counties, were published in the February 1995 issue of Pediatrics.*
Low birthweight babies are 100 times more likely to develop CP than normal birthweight infants. If further research confirms the study's findings, use of magnesium sulfate may prevent 25 percent of the cases of CP in the approximately 52,000 low birthweight babies born each year in the United States.
Magnesium is a natural compound that is responsible for numerous chemical processes within the body and brain. Obstetricians in the United States often administer magnesium sulfate, an inexpensive form of the compound, to pregnant women to prevent preterm labor and high blood pressure brought on by pregnancy. The drug, administered intravenously in the hospital, is considered safe when given under medical supervision.
Scientists speculate that magnesium may play a role in brain development and possibly prevent bleeding inside the brains of preterm infants. Previous research has shown that magnesium may protect against brain bleeding in very premature infants. Animal studies have demonstrated that magnesium given after a traumatic brain injury can reduce the severity of brain damage.
Despite these encouraging research findings, pregnant women should not change their magnesium intake because the effects of high doses have not yet been studied and the possible risks and benefits are not known.
Researchers caution that more research will be required to establish a definitive relationship between the drug and prevention of the disorder. Clinical trials now underway, one of them a collaboration between the NINDS and the National Institute of Child Health and Human Development, are evaluating magnesium for the prevention of cerebral palsy in prematurely born babies.
*Nelson KB, and Grether JK. Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants? Pediatrics, February 1995, vol. 95, no. 2, page 263."
Serum levels of magnesium at birth related to complications of immaturity (1997)
http://onlinelibrary.wiley.com/doi/10.1 ... x/abstract
"Magnesium sulphate given prior to birth to pre-eclamptic mothers and mothers in preterm labour has in retrospect been found to be associated with a decreased incidence of both intraventricular haemorrhage and cerebral palsy."
also, re slow motion stroke:
Low levels of serum ionized magnesium are found in patients early after stroke which result in rapid elevation in cytosolic free calcium and spasm in cerebral vascular muscle cells
http://www.sciencedirect.com/science/ar ... 4097004710
"Ninety-eight patients admitted to the emergency rooms of three urban hospitals with a diagnosis of either ischemic stroke or hemorrhagic stroke exhibited early and significant deficits in serum ionized Mg2+ (IMg2+), but not total Mg, as measured with a unique Mg2+-sensitive ion-selective electrode. Twenty-five percent of these stroke patients exhibited >65% reductions in the mean serum IMg2+ found in normal healthy human volunteers or patients admitted for minor bruises, cuts or deep lacerations..."
take away what you like from this folks

take control of your own health.
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Re: SPASM AND STIFFNESS AS SPASTICITY
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Re: SPASM AND STIFFNESS AS SPASTICITY

take control of your own health.
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Re: SPASM AND STIFFNESS AS SPASTICITY
Magnesium does nothing for cerebral palsy after it has already been present.
The upper motor neuron damage is the only cause of spasticity in MS.
sou
Re: SPASM AND STIFFNESS AS SPASTICITY
call it a co-morbidity, if that's what it takes for it to make sense in your view.
luckily TGFTM's spasticity is quite likely to respond to magnesium therapy, given the circumstances.
take control of your own health.
pursue optimal self care, with or without a diagnosis.
Re: SPASM AND STIFFNESS AS SPASTICITY
The magnesium-deficiency tetany syndrome in man
BL Vallee, WEC Wacker… - New England Journal of …, 1960 - Mass Medical Soc
... On admission carpopedal spasm and a positive Chvostek sign were obvious, but the patient was completely oriented and lucid. The concentration of calcium in serum was normal, but that of magnesium was decreased to 0.94 milliequiv. per liter.
take control of your own health.
pursue optimal self care, with or without a diagnosis.
Re: SPASM AND STIFFNESS AS SPASTICITY
Unfortunately, it can do nothing for the underlying upper neuron damage. This is the reason I doubt that magnesium supplementation can be a solution. Nonetheless, I can't find any solution, whatsoever.
Re: SPASM AND STIFFNESS AS SPASTICITY
it's a pretty cheap supplement to experiment with, as long as you are certain to balance and time it properly with any vitamin d3 in the regimen, especially if you were low in magnesium to start with!
the pharmacist who first recommended magnesium to me said to take some of my daily magnesium with the daily d3, and some at a different time.
nowadays i only take d3 weekly, and magnesium (plus the rest of my supplements including whatever d3 is in my multi) through the rest of the week.
how much mag do you take each day, and what form? do you also take vit d3? do you take the mag with the d3, or at a different time?
take control of your own health.
pursue optimal self care, with or without a diagnosis.
- broomdancer
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Re: SPASM AND STIFFNESS AS SPASTICITY
Re: SPASM AND STIFFNESS AS SPASTICITY
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