CCSVI 2020 - Developmental Venous Anomalies observed in MRI

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CCSVI 2020 - Developmental Venous Anomalies observed in MRI

Post by frodo » Thu May 21, 2020 2:27 am

It is already more than 10 years since the first report They have just found that it can be seen on FLAIR-MRI:

Multiparametric MRI Evaluation of Developmental Venous Anomalies in Brain: Association With Signal Changes on FLAIR in Patients With Multiple Sclerosis



Developmental venous anomalies (DVAs) can be determined on magnetic resonance imaging (MRI), and they may be associated with multiple sclerosis (MS) lesions.


To evaluate the MRI findings of DVAs in the brain, to compare the prevalence of them between MS patients and control subjects, and to investigate the correlation of DVAassociated fluid-attenuated inversion recovery (FLAIR) hyperintensities and MRI-derived parameters between MS patients and control subjects having DVA.


In all, 160 patients with a mean age of 45 ± 16 years who underwent multiparametric MRI including susceptibility-weighted imaging (SWI), diffusion-weighted imaging, 3D FLAIR, and contrast-enhanced imaging were included in this retrospective study. First, the presence of DVA was compared between the MS and control groups using the Chisquare test. Then, among the subjects having DVA, age, gender, and MRI-derived parameters such as signal increase of DVA on FLAIR, location, and drainage of DVA were compared between the MS and control groups using Chi-square test.


The presence of DVA did not differ between the MS and control groups (P = 0.828). Signal increase around DVA on FLAIR (P = 0.03) and the age of less than 45 years demonstrated a significant correlation with MS group (P = 0.022).


In our study, DVAs were effectively detected using SWI and 3D contrast-enhanced T1-weighted imaging on MRI. The signal increase of DVA was better revealed on 3D FLAIR on MRI, and it was the only significant MRI-derived parameter in patients with MS.

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