ponesimod (or gillenia) effects

Gilenya, or Fingolimod, is the first approved oral disease modifying drug for MS.
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zorro8081980
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ponesimod (or gillenia) effects

Post by zorro8081980 » Wed Jan 20, 2016 7:00 pm

I have been proposed to try to take part in ponesimod clinical trial, third phase (without placebo). Ponesimod is a drug made by Actellion, the Swiss pharmaceutical company. That is a drug close to gilenia and RPC1063. they all three sequester lymphocytes into lymph nodes.

Does it worth it? Is gilenia really effective drug? What is the estimated rate of disability slowing? What side effects have to be aware of?

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euphoniaa
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Re: ponesimod (or gillenia) effects

Post by euphoniaa » Thu Jan 21, 2016 6:06 am

zorro8081980 wrote: Does it worth it? Is gilenia really effective drug? What is the estimated rate of disability slowing? What side effects have to be aware of?

Hi zorro,

Here's a link to the entire Gilenya "Full Prescribing Information" :
http://www.pharma.us.novartis.com/produ ... ilenya.pdf
It gives an overall summary at the top, then goes into 24 pages of details -- including summaries of the trials and the pharmacology.

And here is the official "Important Safety Information": http://www.gilenya.com/c/multiple-sclerosis/isi that gives more details about each of Gilenya's most disturbing potential side effects.

And here's a link to the FDA's "Safety Warning" about PML and Gilenya: http://www.fda.gov/Drugs/DrugSafety/ucm456919.htm

As an FYI - ALL prescription medications that I've ever looked up have this information posted right at their websites.

Good luck!
Dx'd with MS & HNPP (hereditary peripheral neuropathy) 7/03 but must have had MS for 30 yrs before that. I've never taken meds for MS except 1 yr experiment on LDN. (I found diet, exercise, sleep, humor, music help me the most.)

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