Aubagio
Aubagio
I began taking Aubagio 14mg yesterday. It was a LONG day. Problems: nausea, dizzyness, runny nose, aches like the flu, headache, chills, etc. It seemed the side effects were a lot like Avonex, but not as severe. This morning I feel relatively normal, but will take my second dose in about 30 minutes.
I tried injections with Avonex and Copaxone, but had huge injection site problems with both, so after a long discussion with my doctor, I agreed to try Aubagio.
Is there anyone out there also taking Aubagio? I would love some feedback from you!
Any thoughts out there on Aubagio?
Thanks!
Re: Aubagio
NHE
Re: Aubagio
Day 2: A little better. Not quite so dizzy, no nausea, still had a headache, but my nose did quit running and the aches weren't so bad.
Day 3: So far today, still have a headache, no nausea, a little dizzier tody...feel a little "out there"....and my feet are swelling and tingling a little. Not sure if that's the aubagio of not. Feel somewhat achy today, but no more than yesterday....hopefully, I'm seeing a light at the end of the tunnel!
Thanks for welcoming to ThisIsMS....
:~)
Re: Aubagio
I had an MRI last November (2011) and my doc wanted to pull me out of the trial then, which indicated to me that I might have been on the placebo when I started but I'm truly guessing. However, since the study was due to go open label in February (and everyone would be getting the same active dose then regardless) I told her I didn't want to be pulled yet and she agreed. I just had another MRI last week and I'll be seeing her in another two weeks so maybe she'll be able to tell if there have been any improvements over last year's MRI or see if we need to look at other options. (The approval on BG-12 has been delayed until sometime next year

I asked my trial coordinator what is going to happen to the extended TOWER study now that Aubagio has been approved by the FDA and she hasn't been told exactly what's going to happen either except that they may continue it until the last person who entered the original TOWER study had completed their initial trial period which would extend it until sometime next year.
Anyway, that's been my experience with Aubagio/teriflunomide and I wish everyone the best of luck with it. It beats the injections by miles!
Have a GREAT day!
Re: Aubagio
Re: Aubagio
Have a GREAT day!

Re: Aubagio

i know it's horribly vain, but the possibility of hair thinning scares me. has anyone experienced this?
Re: Aubagio
Here is my History
I have had MS for 17 years and all but the first three I have been on Avonex
I started the Aubagio Oct 12 at 14mg I was having a pretty rough time so I am now down to 7mg and doing much better, still having a queasy stomach but not nearly as sick as the 14mg. I think it was just to much drug considering Iwas only taking half doses of Avonex when I was on it.
What time of the day do you take your abubagio? and have you found you have less side effects when taken with food?
Do you think there is any with drawl effects from stopping the Avonex?
I asked the nurse about the hair thinning and she says it is not a long lasting symptom so I hope she is right.
Re: Aubagio
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Re: Aubagio

B
Re: Aubagio
For me it is no question, and I will be starting this drug shortly.
The sfx of liver damage is very scary. I only have one liver,
and I know that it's in perfect condition...
I plan on taking the pill after dinner and hopefully I can sleep
through the other stuff, As I am -sure- it will effect me that way.
I feel like I should go out and buy a wig before any hair loss
sets in...
I hate this disease.
I imagine I will track daily stuff on my little blog dealie.
Here goes.
So lucky to have options.
Secondary progressive
14mg aubagio
Edss = 8
Check out my blog!
Laura5myMSstories.blogspot.com
Re: Aubagio
However, it is clearly evident that my hair has thinned substantially and although I still have lots, the strands are very wirey, and my hair is no longer bushy. I have lost some hair, now 57 years old, probably due to age but the thickness of my hair had always more than covered off any signs of hair loss. Now, its not the case. Evidence of my scalp are more apparent.
I was hoping to take a drug holiday this June when the trial was to be over however it has been extended until December 2014. Hope I still have hair by then.
Otherwise, no symptoms whatsoever
- brog64
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Re: Aubagio
I have had fairly horrid nausea with it and headaches but otherwise no other side effects yet. The nausea and headaches are about the same as when I started on Cladribine so I'm hoping it won't last for very long and will ease off as quickly as it did back then too.
I am just thankful to be on a DMD again and doing something to slow down the course of the bloody MS. Having had such a rocky course with DMDs and having had pretty much no treatment for the 10 since diagnosis because of adverse reactions and allergies it is such a relief to hve a drug that hopefully I will be able to tolerate.
My liver enzymes are being closely monitored as they are already elevated due to other medications I have been on which is hardly desirable on Aubagio but with careful monitoring I am willing to accept the risk. I am so disabled and need home help and personal care every day now and I have nearly died twice in the last year with pneumonia and other respiratory complications so I am getting quite desperate to slow this thing down.
Fingers crossed it works and all the best to the others also taking it.... Brave pioneers marking the trail for others

Cheers,
Brog
- lyndacarol
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Re: Aubagio
Hi Belinda (brog64),brog64 wrote:Hi, I have just started Aubagio this week after being drug free for 18 months. I was on Cladribine but Merck pulled it from the market leaving me and about 1500 others in the Cladribine cohort up the creek while we waited for the release of BG12. But BG12 is being delayed again and again so my neuro suggested starting Aubagio under the Product Familiarisation Program run by the drug company and I started 4 days ago.
I have had fairly horrid nausea with it and headaches but otherwise no other side effects yet. The nausea and headaches are about the same as when I started on Cladribine so I'm hoping it won't last for very long and will ease off as quickly as it did back then too.
I am just thankful to be on a DMD again and doing something to slow down the course of the bloody MS. Having had such a rocky course with DMDs and having had pretty much no treatment for the 10 since diagnosis because of adverse reactions and allergies it is such a relief to hve a drug that hopefully I will be able to tolerate.
My liver enzymes are being closely monitored as they are already elevated due to other medications I have been on which is hardly desirable on Aubagio but with careful monitoring I am willing to accept the risk. I am so disabled and need home help and personal care every day now and I have nearly died twice in the last year with pneumonia and other respiratory complications so I am getting quite desperate to slow this thing down.
Fingers crossed it works and all the best to the others also taking it.... Brave pioneers marking the trail for others![]()
Cheers,
Brog
Undoubtedly, you know that my focus is on insulin. And so I encourage you to request a fasting blood insulin test from your GP or internist.
With elevated liver enzymes, have you discussed the possibility of Fatty Liver Disease with your GP? There is a connection between elevated insulin, inflammation, and internal fat around the organs such as the liver.
In the meantime, YOU are a brave pioneer…
Re: Aubagio
Thank you.
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