2018 correspondence - MS Genetics: Overview & New Directions

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2018 correspondence - MS Genetics: Overview & New Directions

Post by jimmylegs » Sun Sep 30, 2018 4:18 am

Genetics of Multiple Sclerosis: An Overview and New Directions
http://perspectivesinmedicine.cshlp.org ... 28951.full

The contribution of genetic inheritance in multiple sclerosis was established early on. Although multiple sclerosis is not a Mendelian disease, its incidence and prevalence is higher in family members of affected individuals compared with the general population. Throughout the last decade, several small studies failed to identify any robust genetic associations besides the classic associations in the major histocompatibility complex region. During the past few years, genome-wide association studies (GWAS) have revolutionized the genetics of multiple sclerosis, uncovering more than 200 implicated genetic loci. Here, we describe these main findings and discuss the new avenues that these discoveries lay open.
take control of your own health
pursue optimal self care at least as actively as a diagnosis
ask for referrals to preventive health care specialists eg dietitians
don't let suboptimal self care muddy any underlying diagnostic picture!

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