several types of alterations in NAWM and NAGM

A forum to discuss research on the origins of MS and its development.
Post Reply
User avatar
frodo
Family Elder
Posts: 1332
Joined: Wed Dec 02, 2009 3:00 pm
Contact:

several types of alterations in NAWM and NAGM

Post by frodo » Sat Mar 23, 2019 4:25 am

Exploring metabolite profiling of patients with secondary progressive multiple sclerosis

http://discovery.ucl.ac.uk/10043414/1/M ... t%20al.pdf


Synopsis

Proton magnetic resonance spectroscopic imaging (MRSI) quantifies brain metabolism in vivo and has the potential of uncovering the mechanism of action of therapeutic drugs.

In this study, we assessed the baseline metabolic profile of 161 patients with secondary progressive multiple sclerosis (SPMS) against a control population by applying a short TE PRESS MRSI protocol at 3T.

Based on the results the SPMS population could be divided into different groups (normal/biochemically abnormal) suggesting biochemical heterogeneity within SPMS patients

Post Reply
  • Similar Topics
    Replies
    Views
    Last post