biomarker for response to IFNbeta

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frodo
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biomarker for response to IFNbeta

Post by frodo » Wed Aug 12, 2020 10:58 am

IFI35 as a biomolecular marker of neuroinflammation and treatment response in multiple sclerosis

https://www.sciencedirect.com/science/a ... 0520309851

Highlights

• No biomarker is available for predicting treatment response and neuroinflammation in Multiple Sclerosis.
• IFI35 increases from the untreated to IFNbeta-1a treated MS patients, compared to HCs.
• IFI35 evidences predictive characteristics respect to lesion burden, WMF and formulation type of IFN.
• IFI35 discriminates the responder to IFN therapy from the non-responder patient.
• IFI35 biological pattern highlights a predictive profile drugs monitoring and innate immunity-dependent neuroinflammation.

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