Short temper

A board to discuss the Multiple Sclerosis modifying drug Rebif
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Short temper

Post by astro » Wed Dec 16, 2009 9:01 pm

Anyone else notice this side effect when taking rebif?

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Re: Short temper

Post by NHE » Thu Dec 17, 2009 12:32 am

Yes. I think that it's a problem common to all of the Ifn-betas. I've found that it's sometimes best to avoid conversations the day after taking my Avonex. It's just too easy to say something that will get interpreted the wrong way.


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Post by Bubba » Thu Dec 17, 2009 3:40 pm

Havent really noticed anything different... But then again, my fuse is generally short anyway. :D

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Post by oreo » Thu Dec 17, 2009 4:33 pm

If by short fused you mean 'highly irritable', don't blame the REBIF. Blame the disease. I attended a local MS support group meeting recently where the speaker was discussing various life-with-MS issues.

When she first started working with the MS clinic, routine visits included the standard question 'Do you ever feel suicidal?'. That was because we MS'ers have a higher than average rate of suicide.

Over the years they noticed that there was more to it. So they added a second question, 'Do you suffer from feelings of depression?' Guess what? Some bright people noticed that a lot of people who become suicidal become depressed first.

Now they have noticed that while some of us suffer from depression, others of us just become downright misserable. When I heard this, I recognized myself. The next day I mentioned it to my spouse and asked her if she thought I was a little short tempered. We won't discuss her reply.

My next visit to my GP, I raised the issue. Seems the treatment for this is pretty much the same as for mild depression. I am now taking 50mg's of Pristiq on a daily basis.

My wife says I am a whole new person - and much nicer than the old one. I know I feel a lot better and in more control. Talk to your doctor. There is no need to suffer issues that can be fixed.
Carpe Diem

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Post by alittletired » Wed Dec 23, 2009 12:42 pm

Good post Oreo!

I recently started on 20mg of citalopram and the difference is huge.
I had never slept well since I started Rebif 6 years ago.
Now I sleep great and am much easier to get along with.

My temper has been cut way back.
I would say my wife is happy I tried it.

One thing though, I am going to try and cut the dose in half after Christmas. I just feel a little numb to life at times.


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Post by Greenfields » Tue Jan 05, 2010 12:05 pm

I've been on Rebif for a year, but I've been a grumpy for years. LOL I had noticed that I was being ....umm impolite to people and I'm trying Wellbutron. I still have the quick to anger issues though.


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Re: Short temper

Post by burntsienna » Tue Jan 19, 2010 11:53 am

astro wrote:Anyone else notice this side effect when taking rebif?
Absolutely! I took Rebif between January and late April last year and each time I titrated up a dose, my temper did too! The anxiety and irritability got so back I had to completely stop taking it. I've had MS for 12 years and a long history of depression and anxiety, but I had never had anything like this. Not even when I was on the Avonex years ago.

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Re: Short temper

Post by brokensailor513 » Sun Oct 14, 2012 8:56 am

You are not the only one who is experiencing this type of feeling. I noticed that I tend to get irritated at the least little things, and that I also snap on people who mention things about MS. These feelings are normal IAW my neurologist, and psychologist. I did a little footwork a few days after being DX, and I found out that many patients have committed suicide.

Staying positive is much harder then people think. It seems like no matter how hard I try to forget that fact that I have MS, someone, or something reminds me..... very, very, frustrating.

A few things that help me control my temper are:
1) place myself in others shoes, and try to view my as they do so that I can understand them
2) Think of how much of a headache that I will get by stressing myself out
3) I usually walk away, or turn music on.

Good luck to you. ; )

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