Summary: This relatively small but interesting study from the UK aimed to assess the utility of McDonald 2010 criteria in comparison with 2007 International Paediatric Multiple Sclerosis Study Group (IPMSSG)-recommended criteria for the diagnosis of paediatric multiple sclerosis (PMS).
The The authors conducted a retrospective analysis of 38 cases of clinically definite relapsing remitting MS from three UK clinics. They found that on baseline scans IPMSSG dissemination in space (DIS) criteria were fulfilled in 68% of scans and McDonald DIS criteria in 84%. The authors therefore suggest that the 2010 McDonald criteria appear more sensitive than IPMSSG and may allow PMS diagnosis at first presentation of CIS in at least a half of cases.... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1408