Impaired toll-like receptor 8 signaling in MS

[MSUK]

Abstract

Background
The etiology and immunopathology of multiple sclerosis (MS) is not well understood. It is recognized that although autoreactive T cells are the main early mediators of disease,

other cell types, including cells of the innate immune system contribute to MS pathogenesis. The objective of this study was to determine if Toll-like receptor (TLR) signaling

is functionally altered in patients with MS..... Read More - http://www.ms-uk.org/index.cfm/immunecells