New article questioning the autoimmune model

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frodo
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New article questioning the autoimmune model

Post by frodo »

No matter how much researchers look at the immune system, they do not find anything unusual. In this article, researchers compare CSF cytokines with other inflammatory diseases controls, and found that MS has even less cytokines than them.

Therefore, all we know is that the standard model is flawed, though we still do not have a better one.

Could it be a good idea to have a subforum about research into MS origin?

Immune Parameters That Distinguish Multiple Sclerosis Patients from Patients with Other Neurological Disorders at Presentation

http://journals.plos.org/plosone/articl ... ne.0135434

Various studies have investigated cytokine levels in the CSF and/or serum of MS patients vs. control groups [22–27]. In these studies different sets of cytokines were measured in mixed MS groups (RR-MS, SP-MS, PP-MS, acute phase, remission, under treatment or not) and various control groups (specific neurological disorders, NIND, IND, healthy controls), with, inevitably, variable results. In general, most of the studies showed elevated inflammatory cytokine levels in MS patients compared to healthy controls, in serum samples mostly [22–27]. However, when MS patients were compared to other IND in general, or with groups of patients with a specific IND (transverse myelitis, neuromyelitis optica, neuro-Beçhet, etc.), IND groups showed higher levels of cytokines compared to MS
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Leonard
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Re: New article questioning the autoimmune model

Post by Leonard »

there is autoimmunity in MS and cytokines will be elevated.
yet our immune system is normal and healthy, nothing unusual.

how this can be explained? see the thesis MS UNRAVELLED on the posting of 10 Aug on http://www.thisisms.com/forum/general-d ... 8-720.html
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