Can brain cell death trigger multiple sclerosis?

[MSUK]

One trigger for multiple sclerosis (MS) might the death of brain cells that make myelin, according to a study published in the journal Nature Neuroscience...Read more - http://www.ms-uk.org/MSnews

[CureOrBust]

http://onlinelibrary.wiley.com/doi/10.1 ... 6/abstract

Relapsing and remitting multiple sclerosis: Pathology of the newly forming lesion

Michael H. Barnett MBBS andJohn W. Prineas MBBS*
Article first published online: 23 FEB 2004

...extensive oligodendrocyte apoptosis and microglial activation in myelinated tissue containing few or no lymphocytes or myelin phagocytes...

And also discussed here on TIMS
http://www.thisisms.com/forum/general-d ... html#p2408

[Leonard]

One trigger for multiple sclerosis (MS) might the death of brain cells that make myelin, according to a study published in the journal Nature Neuroscience...Read more - http://www.ms-uk.org/MSnews

Quote from the article under the link:
The researchers believe that oligodendrocyte death can be caused by a variety of factors, including developmental abnormalities, viruses, bacterial toxins, or environmental pollutants. For human patients, it may not be until years after an initial injury that the brain triggers oligodendrocyte death, the study authors hypothesise.



Of course, they hit the main issue. And it is not an 'or', it is an 'and'.

For a further explanation, see the Thesis MS Unravelled on http://www.thisisms.com/forum/general-d ... 27300.html