respiratory tract nutrition

[jimmylegs]

New insights into the role of zinc in the respiratory epithelium (2001)
https://www.ncbi.nlm.nih.gov/pubmed/11264713

"...This paper will also review studies from the authors’ laboratory concerning the first attempts to map Zn in the respiratory epithelium and to elucidate its role in regulating caspase‐3 activated apoptosis. We propose that Zn, being a major dietary anti‐oxidant has a protective role for the airway epithelium against oxyradicals and other noxious agents. ... "

Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses (2007)
https://www.ncbi.nlm.nih.gov/pubmed/17922955

"...Micronutrients contribute to the body's natural defences on three levels by supporting physical barriers (skin/mucosa), cellular immunity and antibody production. Vitamins A, C, E and the trace element zinc assist in enhancing the skin barrier function. The vitamins A, B6, B12, C, D, E and folic acid and the trace elements iron, zinc, copper and selenium work in synergy to support the protective activities of the immune cells. Finally, all these micronutrients, with the exception of vitamin C and iron, are essential for antibody production. Overall, inadequate intake and status of these vitamins and trace elements may lead to suppressed immunity, which predisposes to infections and aggravates malnutrition."

A randomized controlled trial of zinc supplementation in the treatment of acute respiratory tract infection in Thai children (2019)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548996/

"... The study found that ALRI cessation was faster in children who received zinc supplementation (median (IQR): 3 (2-4) days and 4 (3-5) days, respectively; P=0.008), and that their hospital stay was shorter (mean (SD): 3.8 (1.3) days and 6.1 (3.2) days, respectively; P<0.001) than the placebo group. Zinc supplementation was well-tolerated, and no adverse events were reported. ... "

i like that this ^ study includes before/after zinc status in subjects and controls

Zinc supplementation ameliorates lung injury by reducing neutrophil recruitment and activity (2020)
https://thorax.bmj.com/content/75/3/253.abstract

"...Conclusion Zinc supplementation attenuated LPS-induced lung injury in a murine ALI model. Thus, the usage of zinc-based strategies should be considered to prevent detrimental consequences of respiratory infection and lung damage in risk groups."

[Petr75]

Interesting, thanks.

[jimmylegs]

np