Selected cannabis cultivars modulate glial activation

[Petr75]

2024 May 22
Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, Beer-Sheva, Israel
Selected cannabis cultivars modulate glial activation: in vitro and in vivo studies
https://pubmed.ncbi.nlm.nih.gov/38778343/

Conclusions: While both cannabis cultivars, CN2 and CN4, significantly reduced the severity of the clinical signs throughout the course of the study, they modulated different inflammatory mediators and pathways, probably due to differences in their phytocannabinoid composition. This demonstrates the differential potential of cannabis cultivars differing in chemotype to regulate neuroinflammation and their potential to treat MS.