Oligoclonal Bands in CSF

blitzi · Post by **blitzi** » Thu Sep 17, 2009 7:09 am

Is there any documents of change of Oligoclonal Bands in CSF on patiens who have had procedure?

I assume that this is very important evidence to measure?

sorry for my english skills

mrhodes40 · Post by **mrhodes40** » Thu Sep 17, 2009 7:14 am

Hi Blitzi,
as far as I know no one has documented any results of OCB's. Someone else asked that question a few weeks ago, it is on the minds of MSers looking at this model for certain so maybe some researcher will look at it soon.
marie

Post by **euphoniaa** » Thu Sep 17, 2009 7:38 am

I'm interested in this question myself. I noted the other day that I had always read that O-bands are permanent, so I wondered if that was truly the case. No one answered at that time.

So, I just tried a quick Google query and came up with this Wikipedia quote, which gives a convincing argument against using Wikipedia as a single information source...

From Wikipedia:

"Oligoclonal bands are an important indicator in the diagnosis of multiple sclerosis. Approximately 79%-90% of all patients with multiple sclerosis have permanently observable oligoclonal bands.

The presence of one band (a monoclonal band) is not considered serious and may simply be normal. More bands may reflect the presence of a disease. The bands tend to disappear from the cerebrospinal fluid as a person recovers from the neurological disease."

Anyone else want to answer this question for us?

Wonder if the bands are only permanent as long as MS is permanent? Until now, MS actually HAS been permanent.

chrishasms · Post by **chrishasms** » Thu Sep 17, 2009 7:55 am

Rokkit · Post by **Rokkit** » Thu Sep 17, 2009 8:42 am

So, I just tried a quick Google query and came up with this Wikipedia quote, which gives a convincing argument against using Wikipedia as a single information source...

The section you copied that from was addressing oligoclonal bands in neurologic diseases in general. So, if you recover from the disease (not necessarily MS) then the bands tend to disappear.

Wonder if the bands are only permanent as long as MS is permanent? Until now, MS actually HAS been permanent.

If the bands tend to disappear after recovery from other diseases then I don't see why not. That would be really cool to see those things go away.

Rokkit

CRHInv · Post by **CRHInv** » Thu Sep 17, 2009 7:03 pm

I think it would be interesting too, but I don't want an extra LP.

Rokkit · Post by **Rokkit** » Fri Sep 18, 2009 2:24 am

That's true. I could do without the week long headache.

Rokkit