Nigel,
The following link is to a new page on the upper cervical angle and intervals you might find interesting as it relates to your case. It also relates to Blossom. You both have similar flexion strains in the cervical spine http://www.upright-health.com/upper-cervical-angle.html
CCSVI and CCVBP
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uprightdoc
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civickiller
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I saw my ucc dr and with him measuring my leg lengths, he said they were equal so he thinks my atlas is holding it's alignment. So now once a month to make sure it's holding. I'm gonna get xrayed next time I go see him to verify my atlas is in it's correct position and not just leg length
what sucks is I haven't recovered from what I thought was retracing
what sucks is I haven't recovered from what I thought was retracing
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costumenastional
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neava, I get what you are saying. Noone here ever sayed that chiropractors can cure MS. Just remember that what you are calling alternative treatment is at least treatment while the drugs conventional docs push are worthless shit. No, make that lethal shit.neava wrote:costumenastional
i had ajustments done afew yrs ago, it helped with my leg pain, and hips, but im having more problems now with my neck,
(in nz we have xrays done instead or mri to see if anythings wrong, the problem with that, if you other issues going on it wont show,)
i had a chiroprator tell me i had a break in my lumber region, my mri shows my disks are narrowing)
also my mri showed a chiari malformation, this is also dangerous if having adjustments,
i spoke to a nuero chrioprator not far from my home town, he told me that if he adjustments me, IT COULD KILL ME,
i also suffer from arachnoid cysts in the theoriac region, the NC also told me i could not be adjusted, im too dangerous.
im now waiting for tests on a conditon called cadasil
MS still hasnt been ruled out.
so in some cases adjustments are wonderful, and in others it can cause more damage, i feel with any alternative treatment you do have to be careful,
no disrepect is any chiroprators here, im sure they have helped alot of people, but it does make you question when is it right to have adjustments,
i always got told that your body will do it naturally.
plus you cant change the blue print of your body
i hope it goes well for you and you get the results that your looking for
surgery is abig step, and not one to take lightly,
please keep me informed how it goes
neava
A good chiro could never harm a patient simply cause the purpose of their adjustments is to put the vertebrae back in place whenever this is possible.
The point is that people with serious neurological conditions due to spinal cord problems can AND WILL be helped. Prior to my first and only relapse I was very healthy and this is the reason I am still able to function well and even recover. Dr Flanagan was God sent in my case.
Chiropractic adjustments can help to one extend and this is something all of us must have in mind.
The only reason this thread exists for, is to make sure that people like me can be helped. Not everyone will be helped.
And the question is: how many people in here are like me?
And is it too late for them to gain some benefits by correcting their damaged bone structure?
Now, I can feel that my neck is not as it should be. It s WAY better than before of course but still, it s not normal. If there was a Flanagan back in 2000 when a crashed my damn head I would never have a problem. We are in 2011 though and I started chiro treatment only a few months back and after my body exploded. And this is the only reason I still have drawbacks. It s a f@@@ switch we are talking here. I am open for surgery if a good surgeon tells me that I should do it. If not, I can live with it, thanks to chiropractic adjustments. That simple.
Don't trust doctors. They dont have a fucking clue. Upon diagnosis I had ANAs, oligoclonal bands and all kinds of shit. It s only natural for my body to produce them given the fact I was living with a seriously damaged neck. They tagged me with MS in a blink of an eye and only thing they cared was which one of them would prescribe ms drugs to me so he would take the money from the pharmas. I spit on their graves.
There is a reason your bodies react like that. It s your job to try to find it and this is just a place for some of us to solve their problem. Not all of us. Just some.
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civickiller
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my whole body just got weak, think every muscle you use. Arms,legs,breathing,abs I can't even hold myself up to sit upright in a chair.uprightdoc wrote:Hello Civickiller,
What are the symptoms you thought were due to retracing? How is you leg strength?
If possible let me see your pre and post x-rays.
I slowly have been getting some strength back
I'll post up my xrays a month from now when I go back. He didn't take post xray so I'm gonna have him take xrays next time I go see him
Another fine article, thanks Dr. The upright MRI has so much to offer.
http://www.upright-health.com/upper-cervical-angle.html
The Upper Cervical Angle
The upper cervical angle and intervals are important to the health and function of the brainstem and cord. The brain scan below is from a case study by Drs. Milhorat, Bolognese and Nishikawa published in the Journal of Neurology in December 2007, using a Fonar Upright MRI in evaluating excess motion in the upper cervical spine.
This particular case was affected by an inherited disorder of connective tissue called Ehler's-Danlos. Among other things, Ehler's-Danlos is associated with loose ligaments predisposing joints to strains, subluxations and dislocations. The excess motion in the upper cervical spine can cause neurological signs and symptoms.
The upper cervical angle, technically known as the clivoaxial angle, is determined by drawing a line along the base of the skull (clivus) and a second line down the backside of the body of the second cervical vertebra (axis) and measuring the degrees of separation between them. The angle is noted as CXA on the brain scan below and should be approximately 140 degrees.
The intervals are critical spaces that separate the base of the skull from the upper cervical spine, as well as spaces between the atlas (C1) and axis (C2) vertebrae of the upper cervical spine. The two spaces in the brain scan are denoted as BDI and BAI and will be explained further below.
The atlas vertebra (C1) of the upper cervical spine connects to the condyles of the posterior fossa of the base of the skull. The front border of the posterior fossa is called the clivus portion of the base of the skull. It is represented by line C in the brain scan above. The brainstem lies parallel to the clivus. (The following link is to a page on this site that discusses the design and angles of the posterior fossa).
The pitch of the clivus varies in different races and in different individuals. In certain cases its pitch is too flat, platybasia, which predisposes the brain to a Chiari malformation when the head is tilted forward. A Chiari malformation occurs when the bottom of the brain comes in contact with the base of the cranial vault.
In addition to the angle of the base of the skull and the pitch of the clivus, the angle of the clivus relative to the upper cervical spine, clivoaxial angle (CXA) mentioned above and shown in the brain scan above, is also important. The pitch of the upper cervical spine is represented by line D drawndown the backside of the odontoid process of the axis or second cervical vertebra (C2). The odontoid, also known as the dens, is the upward pointing tooth-like projection as seen in the sketch below of the axis (C2).
In contrast to the clivoaxial angle, the upper cervical intervals are several specific spaces between certain points of the base of the skull and upper cervical spine, and between the upper cervical vertebrae atlas (C1) and axis (C2).
Conditions Resulting from Changes in Angles and Intervals
It is important to maintain a proper angle and spacing between the base of the skull and the upper cervical spine to prevent compression problems of the brainstem and cord. Decreases in the upper cervical angle and intervals in relationship to the base of the skull have been associated with respiratory problems in rheumatoid arthtitis, autism in children and brainstem signs and symptoms in Ehler's-Danlos and Chiari malformations. In addition to the above, decreases in the upper cervical angle and base of the skull may play a role in Alzheimer’s, Parkinson’s and multiple sclerosis, as well as other neurodegenerative diseases.
Some of the design problems that affect the intervals and upper cervical angles to the base of the skull are genetic (inherited). Consequently, beginning signs and symptoms associated with the condition tend to show up earlier in life. In other cases, the normal upper cervical angle and intervals are decreased by misalignments in the upper cervical spine due to aging, injuries and trauma.
In either case, a decrease in the normal upper cervical angle and intervals can kink the brainstem and cord, compress the contents of the foramen magnum and spinal canal, and cause Chiari malformations. In addition to the spinal cord, the contents of the foramen magnum also include: 1)the vertebral veins, which drain the brain during upright posture; 2)the vertebral arteries, which supply blood to the brainstem, cerebellum and inner aspects of the temporal and occipital lobes of the brain; and 3) the subarachnoid space of the cord, which contains cerebrospinal fluid (CSF) and is continuous with the cisterns of the brain.
As mentioned, the normal upper cervical angle or clivoaxial angle, should be about 140 degrees. As seen on the right side in the brain scan above, when the clivoaxial angle falls below the normal range it causes a kink or kyphosis in the spinal cord. This is similar to the kinking of the brainstem caused by platybasia (flatter than normal base of the skull). The area of the spinal cord affected by a less than normal angle is called the cervicomedullary connection. It is the connection between the upper cervical spinal cord and the lower end of the brainstem. In addition to kinking the cord, a decrease in the clivoaxial angle also predisposes the brainstem to compression by a functional Chiari malformation likewise similar to platybasia.
As mentioned above, the intervals or distances between the upper cervical spine and the clivus and other points on the base of the skull and between C1 and C2 are, likewise, important. One of the important intervals is the distance between the bottom of the clivus called the basion, and the tip of the dens (odontoid process) of C2. In the brain scan above the basion-dens interval is noted as BDI. There are other important intervals radiologists check as well.
Basilar invagination, also called basilar impression, occurs when the odontoid process of C2 actually penetrates the foramen magnum. In cases with basilar invagination there is no BDI. Basilar invagination is the opposite of a Chiari malformation in which the brainstem and cerebellum descend into the foramen magnum. Instead, in basilar invagination the odontoid either pushes up into the foramen magnum or the skull sinks down onto it, which is called cranial settling. In either case the odontoid process penetrates the foramen magnum. The consequence is compression of the cervicomedullary junction between the medulla at the lower end of the brainstem and the upper end of the cervical portion of the spinal cord.
Several genetic conditions and acquired diseases can cause basilar invagination or impression. For example, different types of design flaws in the upper cervical spine can cause it such as Kleppel-Feil in which the neck is too short. Endocrine diseases such as Morquios (dwarfism) and cleidocraniodysostosis (failure of cartilage conversion to bone during development) can also cause it. In adults Marfans (giantism) and Paget’s disease (enlarged head size), also cause changes in bone with similar outcomes.
Inherited disorders of connective tissues such as rheumatoid arthritis and Ehler’s-Danlos syndrome can cause ligament laxity and subsequent upper cervical instability called atlantoaxial instability. Atlantoaxial instability can result in cranial settling and basilar invagination. In the brain scan above the scan on the left was done with the patient lying down in the supine, face-up, position. The scan of the right is with the patient sitting up.
In this particular case, both the upper cervical angle and the intervals relative to the base of the skull decreased when the patient sat up. Rather than the cerebellum descending into the foramen magnum in a classic type Chiari malformation, in this case the upper cord gets kinked and the front side of the lower brainstem comes in contact with the clivus of the base of the skull and the cerebellum comes in contact with the floor of the posterior fossa.
As upright MRI becomes more commonly used we will, more than likely, see more of these types of situations. Chiari type malformations in which parts of the brain come in contact with the floor of the cranial vault or penetrate its foramen are probably more common than we think and the source of many neurological and neurodegenerative conditions we now see.
http://www.upright-health.com/upper-cervical-angle.html
The Upper Cervical Angle
The upper cervical angle and intervals are important to the health and function of the brainstem and cord. The brain scan below is from a case study by Drs. Milhorat, Bolognese and Nishikawa published in the Journal of Neurology in December 2007, using a Fonar Upright MRI in evaluating excess motion in the upper cervical spine.
This particular case was affected by an inherited disorder of connective tissue called Ehler's-Danlos. Among other things, Ehler's-Danlos is associated with loose ligaments predisposing joints to strains, subluxations and dislocations. The excess motion in the upper cervical spine can cause neurological signs and symptoms.
The upper cervical angle, technically known as the clivoaxial angle, is determined by drawing a line along the base of the skull (clivus) and a second line down the backside of the body of the second cervical vertebra (axis) and measuring the degrees of separation between them. The angle is noted as CXA on the brain scan below and should be approximately 140 degrees.
The intervals are critical spaces that separate the base of the skull from the upper cervical spine, as well as spaces between the atlas (C1) and axis (C2) vertebrae of the upper cervical spine. The two spaces in the brain scan are denoted as BDI and BAI and will be explained further below.
The atlas vertebra (C1) of the upper cervical spine connects to the condyles of the posterior fossa of the base of the skull. The front border of the posterior fossa is called the clivus portion of the base of the skull. It is represented by line C in the brain scan above. The brainstem lies parallel to the clivus. (The following link is to a page on this site that discusses the design and angles of the posterior fossa).
The pitch of the clivus varies in different races and in different individuals. In certain cases its pitch is too flat, platybasia, which predisposes the brain to a Chiari malformation when the head is tilted forward. A Chiari malformation occurs when the bottom of the brain comes in contact with the base of the cranial vault.
In addition to the angle of the base of the skull and the pitch of the clivus, the angle of the clivus relative to the upper cervical spine, clivoaxial angle (CXA) mentioned above and shown in the brain scan above, is also important. The pitch of the upper cervical spine is represented by line D drawndown the backside of the odontoid process of the axis or second cervical vertebra (C2). The odontoid, also known as the dens, is the upward pointing tooth-like projection as seen in the sketch below of the axis (C2).
In contrast to the clivoaxial angle, the upper cervical intervals are several specific spaces between certain points of the base of the skull and upper cervical spine, and between the upper cervical vertebrae atlas (C1) and axis (C2).
Conditions Resulting from Changes in Angles and Intervals
It is important to maintain a proper angle and spacing between the base of the skull and the upper cervical spine to prevent compression problems of the brainstem and cord. Decreases in the upper cervical angle and intervals in relationship to the base of the skull have been associated with respiratory problems in rheumatoid arthtitis, autism in children and brainstem signs and symptoms in Ehler's-Danlos and Chiari malformations. In addition to the above, decreases in the upper cervical angle and base of the skull may play a role in Alzheimer’s, Parkinson’s and multiple sclerosis, as well as other neurodegenerative diseases.
Some of the design problems that affect the intervals and upper cervical angles to the base of the skull are genetic (inherited). Consequently, beginning signs and symptoms associated with the condition tend to show up earlier in life. In other cases, the normal upper cervical angle and intervals are decreased by misalignments in the upper cervical spine due to aging, injuries and trauma.
In either case, a decrease in the normal upper cervical angle and intervals can kink the brainstem and cord, compress the contents of the foramen magnum and spinal canal, and cause Chiari malformations. In addition to the spinal cord, the contents of the foramen magnum also include: 1)the vertebral veins, which drain the brain during upright posture; 2)the vertebral arteries, which supply blood to the brainstem, cerebellum and inner aspects of the temporal and occipital lobes of the brain; and 3) the subarachnoid space of the cord, which contains cerebrospinal fluid (CSF) and is continuous with the cisterns of the brain.
As mentioned, the normal upper cervical angle or clivoaxial angle, should be about 140 degrees. As seen on the right side in the brain scan above, when the clivoaxial angle falls below the normal range it causes a kink or kyphosis in the spinal cord. This is similar to the kinking of the brainstem caused by platybasia (flatter than normal base of the skull). The area of the spinal cord affected by a less than normal angle is called the cervicomedullary connection. It is the connection between the upper cervical spinal cord and the lower end of the brainstem. In addition to kinking the cord, a decrease in the clivoaxial angle also predisposes the brainstem to compression by a functional Chiari malformation likewise similar to platybasia.
As mentioned above, the intervals or distances between the upper cervical spine and the clivus and other points on the base of the skull and between C1 and C2 are, likewise, important. One of the important intervals is the distance between the bottom of the clivus called the basion, and the tip of the dens (odontoid process) of C2. In the brain scan above the basion-dens interval is noted as BDI. There are other important intervals radiologists check as well.
Basilar invagination, also called basilar impression, occurs when the odontoid process of C2 actually penetrates the foramen magnum. In cases with basilar invagination there is no BDI. Basilar invagination is the opposite of a Chiari malformation in which the brainstem and cerebellum descend into the foramen magnum. Instead, in basilar invagination the odontoid either pushes up into the foramen magnum or the skull sinks down onto it, which is called cranial settling. In either case the odontoid process penetrates the foramen magnum. The consequence is compression of the cervicomedullary junction between the medulla at the lower end of the brainstem and the upper end of the cervical portion of the spinal cord.
Several genetic conditions and acquired diseases can cause basilar invagination or impression. For example, different types of design flaws in the upper cervical spine can cause it such as Kleppel-Feil in which the neck is too short. Endocrine diseases such as Morquios (dwarfism) and cleidocraniodysostosis (failure of cartilage conversion to bone during development) can also cause it. In adults Marfans (giantism) and Paget’s disease (enlarged head size), also cause changes in bone with similar outcomes.
Inherited disorders of connective tissues such as rheumatoid arthritis and Ehler’s-Danlos syndrome can cause ligament laxity and subsequent upper cervical instability called atlantoaxial instability. Atlantoaxial instability can result in cranial settling and basilar invagination. In the brain scan above the scan on the left was done with the patient lying down in the supine, face-up, position. The scan of the right is with the patient sitting up.
In this particular case, both the upper cervical angle and the intervals relative to the base of the skull decreased when the patient sat up. Rather than the cerebellum descending into the foramen magnum in a classic type Chiari malformation, in this case the upper cord gets kinked and the front side of the lower brainstem comes in contact with the clivus of the base of the skull and the cerebellum comes in contact with the floor of the posterior fossa.
As upright MRI becomes more commonly used we will, more than likely, see more of these types of situations. Chiari type malformations in which parts of the brain come in contact with the floor of the cranial vault or penetrate its foramen are probably more common than we think and the source of many neurological and neurodegenerative conditions we now see.
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uprightdoc
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Hello CN,
Your right. Chiropractors don't cure MS but neither do drugs or surgery. By the time symptoms show up many MS cases are already associated with permanent structural and neurological damage. In your case you over stretched and tore connective tissues that hold the spine in its proper position. Chiropractic, like drugs and surgery can help in the management of MS by restoring function to the spine and taking the pressure off of the nervous system. It may also help in prevention, or at least limit the damage in cases like yours. If the spine was a self- correcting mechanism, your spine as well as, Nigel, Blossom, Poet and the whole lot of you would have self repaired years ago.
Your right. Chiropractors don't cure MS but neither do drugs or surgery. By the time symptoms show up many MS cases are already associated with permanent structural and neurological damage. In your case you over stretched and tore connective tissues that hold the spine in its proper position. Chiropractic, like drugs and surgery can help in the management of MS by restoring function to the spine and taking the pressure off of the nervous system. It may also help in prevention, or at least limit the damage in cases like yours. If the spine was a self- correcting mechanism, your spine as well as, Nigel, Blossom, Poet and the whole lot of you would have self repaired years ago.
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ccsvi
thank you nigel. i too think of you and the others. hopefully we will get some relief. i do hope that more check this out and the early diagnosed will be spared a lot of unnecessary suffering.
The Blood Brain Barrier--putting the pieces together
by CCSVI in Multiple Sclerosis on Tuesday, May 31, 2011 at 11:48am
We've been discussing how Lyme bacteria and the JC virus can harm and destroy brain tissue....but what allows these infectious agents into brain tissue in the first place? If the blood brain barrier were functioning correctly, these agents would not be an issue. They just wouldn't be able to harm the brain.
The Blood Brain Barrier (BBB) is very important in keeping circulating blood out of brain tissue.
The common wisdom is that in MS, the BBB is being breached in some mysterious fashion by T-cells that are punching thru and randomly attacking myelin in the MS brain.
Current definition:
The blood-brain barrier is the semipermeable layer of cells within the capillaries of the central nervous system. When functioning normally, the blood-brain barrier prevents foreign invaders (such as viruses) and immune cells from passing out of the bloodstream and into the central nervous system. It also allows oxygen and essential nutrients to enter the central nervous system.
In multiple sclerosis, immune cells are allowed to enter the central nervous system, implying that the blood-brain barrier is damaged or compromised in some way. These immune cells, called T lyphocytes, attack the myelin in the brain and spinal cord, causing the lesions which lead to MS symptoms.
http://ms.about.com/od/glossary/g/blood_brain.htm
But what if those t-cells are being invited to cross over due to an already breeched BBB? What if it is CCSVI creating a break in this barrier? We already have a known model for how this happens.....
Here is a wonderful hypothesis paper on how raised venous pressure affects the tight junctions of the endothelium and allows a break in the BBB. It was written in 2007, before Dr. Zamboni published his research on the extracranial venous blockages he found in CCSVI, and was inspired by the work of Dr. Schelling. It uses the example of how dural arteriovenous fistulas (DAVFs) block veins and increase venous pressure, causing tight junctions to separate and t-cells to slip through and create myelopathy. Just like MS.....
So, is the break in the BBB caused by some mysterious event where t-cells suddenly punch through and attack myelin OR could the break in the BBB be caused by raised venous pressure and an opening up of the tight junctions---just like it is in a dural arteriovenous fistula???
Once again, Ockham's Razor comes to mind....
I recommend reading the complete paper for a full understanding of the hypothesis. Here's the link:
http://www.direct-ms.org/sites/default/ ... S%2008.pdf
Here's a bit of the paper to get you interested....
Raised venous pressure as a factor in multiple sclerosis
David G. Talbert *
Institute of Reproductive and Developmental Biology, Imperial College School of Medicine, Du Cane Road,
London W12 ONN, United Kingdom
Received 22 September 2007; accepted 6 October 2007
Summary-- It is hypothesised that the inflammatory condition seen in MS and the progressive myelopathy that is being successfully halted by obliteration of dural arteriovenous fistulas (DAVFs), may actually be two sides of the same coin.
Excessive venous hypertension can stretch vein walls sufficiently to separate the tight junctions between endothelial cells forming the blood-brain-barrier (BBB). Colloids, etc., but not necessarily erythrocytes, could then pass through the exposed porous basement membranes. The resulting changes in osmotic pressure, etc. would disrupt the axon and dendrite internal transport systems, leading to their disintegration. The normal inflammatory processes which would follow, might be indistinguishable from those associated with autoimmune disease.
Ascending progressive myelopathy and disablement are associated with an intracranial DAVF when its outflow enters the spinal venous system and descends past the cervical region. This can be arrested, and some degree of recovery produced, if the DAVF can be successfully eliminated or blocked. However, if the DAVF outflow is entirely into the spine, intracranial venous pressure may be normal and so there is nothing to alert the clinician to the presence of an intracranial DAVF.
It is suggested that where spinal MS has been diagnosed from clinical observations, patients should be referred for angiological investigation to search for DAVFs within the head to identify any treatable subjects.
c 2007 Elsevier Ltd. All rights reserved.
Introduction
MS relation to veins
Multiple sclerosis (MS) is characterized by multiple plaques of demyelination within the brain and/or
spinal cord, currently attributed to an autoimmune process, following some as yet unidentified event.
Close relatives have increased chance of developing MS, but no known links exist between MS and any
infection [1]. Early investigators noted that plaques formation was not completely random. In the spine
there appeared to be an underlying segmental pattern. Plaques in the CNS generally appear to be related
to veins. Tan et al. [2] studied 95 brain MS lesions using magnetic resonance imaging (MRI) techniques in vivo. They found a central vein was visible in all but one. The lesions typically had a basically ovoid shape whose long axis correlated well with the course of the vein, whereas using the same technique on cases of hypoxic ischemic white matter, lesions bore no relationship to venous patterns. Kidd et al. [3] found large cortical lesions, which pass around gyri, were likely to reflect involvement of the central vein of the gyrus.
Sources of spinal venous hypertension
Retinopathy and optic nerve pathology are frequent early clinical signs of MS but also occur with acute raised intrathoracic pressure as blood is forced back into the head producing surges of intracranial venous pressure (‘Valsalva retinopathy’) [4–13] . Apart from such acute events, chronic venous hypertension may result from arteriovenous anastomoses (AVA), in particular dural arteriovenous fistulas (DAVFs), within the head [14,15] or spine [16] . Borden et al. [17] recognised the various pathological significances of the drainage paths of intracranial dural arteriovenous fistulas (DAVFs). They suggested three categories; type I draining entirely within the skull, type III draining entirely into the spinal venous system, and type II with mixed drainage. Using in vivo magnetic resonance imaging (MRI), Kwon et al. [18] observed that distension of ophthalmic veins occurs in grade II but not in grade III. In contrast spinal dilated leptomeningeal or medullary vessels were not seen in grade I, but were in 100% of grade III cases. Cognard et al. [15] found that in cases where drainage was purely spinal, progressive myelopathy occurred in 50% of cases. Brunereau et al. [14] compared two such spinal drainage groups and found that where grade III drainage could be traced to the lumbar region it was clinically associated with slowly progressing ascending myelopathy involving first the lower and then the upper limbs. On the other hand, where drainage could only be traced as far as the cervical region of the cord, myelopathy did not seem to occur. Fistulas associated with myelopathy also occur in the spinal vasculature, where they may be recognised by the occurrence of reversed or severely reduced local spinal vein flows.
The strong clinical links between disability and factors producing CNS venous hypertension, raises the
possibility that the unknown initial event [1] might be mechanical.
Hypothesis
That the initial event in one form of MS is endothelial cell tight junction separation due to radial distension of veins in the head and/or spine by excessively raised transmural pressures. Overt failure of the vein wall may not occur, but separation of endothelial tight junctions would result in local breaching of the blood-brain-barrier (BBB). The resulting changes in osmotic pressure, pH, Na/K balance etc. would then disable the intra-axon and intra-dendritic transport systems, on which these cell extensions depend for normal function, leading to their degeneration. This in turn would trigger an intensive but completely normal inflammatory scavenging reaction, secondary to the primary damage caused by disruption of the BBB.
Hence, anti-inflammatory treatments would have no effect on the incidence of this form of MS. Arteriovenous anastomoses of various kinds, or venous obstruction would provide the underlying chronic
venous hypertension.
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uprightdoc
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Terrific stuff Nigel.
I would have to agree with Schelling's hypothesis regarding venous backjets as the source of excessive venous back pressure that stretches the BBB and damages myelin. It makes the most sense. It's the only theory that can explain the peculiar location and nature of the lesions as well as enviornmental and racial differences in the incidence of MS.
I would have to agree with Schelling's hypothesis regarding venous backjets as the source of excessive venous back pressure that stretches the BBB and damages myelin. It makes the most sense. It's the only theory that can explain the peculiar location and nature of the lesions as well as enviornmental and racial differences in the incidence of MS.
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uprightdoc
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Civickiller,civickiller wrote:my whole body just got weak, think every muscle you use. Arms,legs,breathing,abs I can't even hold myself up to sit upright in a chair.uprightdoc wrote:Hello Civickiller,
What are the symptoms ... due to retracing? If possible let me see your pre and post x-rays.
I slowly have been getting some strength back
I'll post up my xrays a month from now when I go back. He didn't take post xray so I'm gonna have him take xrays next time I go see him
Does your neurologist ever test your arm, wrist, hand, leg and foot muscles when you complain of weakness? If so, what are the typical findings?
Hi everyone.
I thought I should put up my two cents worth on Marie Rhodes book, CCSVI as the Cause of Multiple Sclerosis. I am about half way through and I am excited by the work that Marie has done in putting the details of CCSVI and MS into one understandable place.
The referencing is very good and thorough.
I especially like the breadth of information that is used to round out the full picture of our health challenges.
There are many parts of the book that cover the similar work to Dr. Flanagan and the references to support them. It is a validation of the work that so many specialists have done and for those who went unnoticed it will re-kindle the flame and give acknowledgement to the science used by these pioneers.
Dr. F have you a copy?
Regards all,
Nigel
I thought I should put up my two cents worth on Marie Rhodes book, CCSVI as the Cause of Multiple Sclerosis. I am about half way through and I am excited by the work that Marie has done in putting the details of CCSVI and MS into one understandable place.
The referencing is very good and thorough.
I especially like the breadth of information that is used to round out the full picture of our health challenges.
There are many parts of the book that cover the similar work to Dr. Flanagan and the references to support them. It is a validation of the work that so many specialists have done and for those who went unnoticed it will re-kindle the flame and give acknowledgement to the science used by these pioneers.
Dr. F have you a copy?
Regards all,
Nigel
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uprightdoc
- Family Elder
- Posts: 1995
- Joined: Thu Sep 30, 2010 2:00 pm
- Location: USA
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