bizarre!
interesting that your hubby has low d in spite of living in cali and having an indoor light and taking supplements.
what is his total current daily equivalent intake from all sources? what is his seasonal range of serum 25-hydroxyvitaminD3 levels?
all things vitamin D
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cheerleader
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Hey Jimmylegs-
I should clarify, sorry! Hubby had low levels at presentation, but he's at normal high levels now. He had malabsorption issues, mild steatorrhea, high liver enzymes and was really toxic at first flare. His GP tested everything, and was very thorough. (Neuro said this wasn't related to MS, but I disagree.) We got him on a probiotic, cut out artificial sweeteners (he was addicted to diet sodas) and got him on a whole food/organic diet without dairy. Did a liver cleanse, and the enzymes resolved themselves in a month. Bowels became normal in a few months.
The vitamin issues have resolved over the course of a year. Our GP keeps testing his serum levels for vitamins, enzymes and hormones. I love her! His B12, D, uric acid are all high normal now, so he's on a maintenance of 2,000 iu vit. D. I'm not sure what his total intake levels of D-3 are, but he's absorbing vitamins now, and we've healed his gastric issues.
I think these gastro problems relate to his MS directly, although our neuro disagrees. She has remarked that he is doing quite well, however-
hope this helps,
AC
I should clarify, sorry! Hubby had low levels at presentation, but he's at normal high levels now. He had malabsorption issues, mild steatorrhea, high liver enzymes and was really toxic at first flare. His GP tested everything, and was very thorough. (Neuro said this wasn't related to MS, but I disagree.) We got him on a probiotic, cut out artificial sweeteners (he was addicted to diet sodas) and got him on a whole food/organic diet without dairy. Did a liver cleanse, and the enzymes resolved themselves in a month. Bowels became normal in a few months.
The vitamin issues have resolved over the course of a year. Our GP keeps testing his serum levels for vitamins, enzymes and hormones. I love her! His B12, D, uric acid are all high normal now, so he's on a maintenance of 2,000 iu vit. D. I'm not sure what his total intake levels of D-3 are, but he's absorbing vitamins now, and we've healed his gastric issues.
I think these gastro problems relate to his MS directly, although our neuro disagrees. She has remarked that he is doing quite well, however-
hope this helps,
AC
I got on a Vitamin D kick for a while, thinking it would make me feel good. All that happened when I took high levels of D was, my hands remembered how numb they were on my last flare up. Thus, I dropped high levels of D and now only get a regular amount.
No vitamin ever made any difference in me that I noticed.
I'm sticking to my NAG, Chondroitin and Acetyl-Carnitine for now.
I'm feeling good more than feeling bad and that's good enough for me.
No vitamin ever made any difference in me that I noticed.
I'm sticking to my NAG, Chondroitin and Acetyl-Carnitine for now.
I'm feeling good more than feeling bad and that's good enough for me.
Vit D as an immune modulator in MS, a review
The researchers state that vitamin D supports a T-cell shift towards an anti-inflamatory profile and enhance regulatory T-cell functionality:
http://www.ncbi.nlm.nih.gov/pubmed/18177949
--Frank
http://www.ncbi.nlm.nih.gov/pubmed/18177949
--Frank
Treatment: Gilenya since 01/2011, CCSVI both IJV ballooned 09/2010, Tysabri stopped after 24 Infusions and positive JCV antibody test, after LDN, ABX Wheldon Regime for 1 year.
it's true you need to be careful about which vitamins you take, in what doses, with which other supplements present. personally, i've been in the habit of reading, forming hypotheses about deficiency based on my diet and lifestyle, then testing levels and either finding or not finding a problem, and where there is a problem i undertake steps to correct the deficiency. sometimes when the lab result indicates no problem, further investigation in the literature has demonstrated that the lab is somewhat off and that "normal" ranges are certainly not "optimal" ranges.
sometimes i have tried supplements based only on symptoms and have been rewarded with radical improvement in under a week. other times it takes me longer to nail down the right blend to resolve a symptom. i still haven't fixed my carpal tunnel syndrome, but it does seem to be a little better these days, in terms of the numbness being there, but not as much of the swollen stiff feeling. i'm not hitting it particularly hard with anything right now though.
with vitamin d in particular you do need to be careful to take things in conjunction with it and if you don't, you can deplete needed minerals in the d absorption process. i suspect that my recent problems that were resolved with magnesium supplementation could have been due to an imbalance in the ratio of calcium and magnesium to my daily d3 intake. i haven't been able to find good research on balancing mg and d3 dosage yet.
sometimes i have tried supplements based only on symptoms and have been rewarded with radical improvement in under a week. other times it takes me longer to nail down the right blend to resolve a symptom. i still haven't fixed my carpal tunnel syndrome, but it does seem to be a little better these days, in terms of the numbness being there, but not as much of the swollen stiff feeling. i'm not hitting it particularly hard with anything right now though.
with vitamin d in particular you do need to be careful to take things in conjunction with it and if you don't, you can deplete needed minerals in the d absorption process. i suspect that my recent problems that were resolved with magnesium supplementation could have been due to an imbalance in the ratio of calcium and magnesium to my daily d3 intake. i haven't been able to find good research on balancing mg and d3 dosage yet.
and i have not seen any research to my recollection that talks about vitamin d reversing nerve damage, just that it affects the immune system and has been shown to reduce relapse frequency. i don't have time to go back over the literature but i don't imagine the assessment methodology is much different from tests on pharmaceuticals and relapse rates. i'm still quite happy to aim for a serum level of 150 and i know my tendency is more in the 70s, even when supplementing. i have to supplement a HUGE amount to get up to 150 and have never felt any ill effects.
and by ill effects i mean in the short term. as previously mentioned, i am suspicious that some of my more recent issues were resolved with magnesium pills, after long term (almost 2 years) supplementation with thousands of units of d per day, including the initial booster of 50,000 per day for 10 days.
Re: Study questions Vit D intake
I recently posted on this topic in another thread. It might be relevant to the present discussion.
NHE
NHE
Last edited by NHE on Tue Jan 29, 2008 1:23 pm, edited 1 time in total.
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SarahLonglands
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Maybe NHE has been highjacked since this thread which was supposed to recently posted is dated only today.
Apart from this, "Dr. Marshall", who has a doctorate in chemical engineering, from before he moved to California and cured himself from sarcoidosis, should bear in mind that in the nineteenth century, some children used to suffer greatly from rickets, now unknown in the civilised world. This was caused by never seeing daylight, never mind sunlight, from one year to the next. They were the mill workers and young lads sent up chimneys and down the mines. They suffered from a severe vitamin D deficiency for this reason.
Also, before the introduction of the first antibiotics, people with TB who were sent to the big TB sanatoriua, were wheeled out of doors in rthe summer and left in the sun. Many of them were cured from the disease.
This is a good link:
http://www.canceractive.com/page.php?n=344#8
Sarah
Apart from this, "Dr. Marshall", who has a doctorate in chemical engineering, from before he moved to California and cured himself from sarcoidosis, should bear in mind that in the nineteenth century, some children used to suffer greatly from rickets, now unknown in the civilised world. This was caused by never seeing daylight, never mind sunlight, from one year to the next. They were the mill workers and young lads sent up chimneys and down the mines. They suffered from a severe vitamin D deficiency for this reason.
Also, before the introduction of the first antibiotics, people with TB who were sent to the big TB sanatoriua, were wheeled out of doors in rthe summer and left in the sun. Many of them were cured from the disease.
This is a good link:
http://www.canceractive.com/page.php?n=344#8
Sarah
An Itinerary in Light and Shadow Completed Dr Charles Stratton / Dr David Wheldon abx regime for aggressive secondary progressive MS in June 2007, after four years. Still improving with no relapses since starting. Can't run but can paint all day.
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cheerleader
- Family Elder
- Posts: 5361
- Joined: Mon Sep 10, 2007 2:00 pm
- Location: southern California
Terrific link, Sarah...
interesting to read that vitamin D acts more like a hormone, and its synergy with vit. A and E.
The only time my sunny Californian husband's vitamin D levels were compromised was at the time of his MS diagnosis last year. He was very sick.... jaundiced, numb, toxic and had very high liver enzymes. Since we've healed his gastric and liver issues, he is absorbing and utilizing vitamins again, as shown by recent serum level testing. I think toxic overload and bacteria were hampering his absorption. Haven't had mineral levels tested, Jimmylegs.
From Sarah's link-
Sunlight on our skin is now thought to be the main 'source' of vitamin D. Whilst a little is found in dairy, the major source is fish liver oils and particularly cod liver oil. Plants contain very little vitamin D. Kidney or liver disease (and alcohol) depress vitamin D levels, as do cholesterol-lowering drugs (e.g. statins), mineral oils, anticonvulsants and toxic chemicals in the environment (e.g. smog). Cadmium blocks vitamin D production whilst pantothenic acid helps make it. Night shift workers have lowered blood levels of vitamin D. Heavily tanned, or black people cannot make vitamin D through the process of sunlight in their skin.
interesting,
AC
interesting to read that vitamin D acts more like a hormone, and its synergy with vit. A and E.
The only time my sunny Californian husband's vitamin D levels were compromised was at the time of his MS diagnosis last year. He was very sick.... jaundiced, numb, toxic and had very high liver enzymes. Since we've healed his gastric and liver issues, he is absorbing and utilizing vitamins again, as shown by recent serum level testing. I think toxic overload and bacteria were hampering his absorption. Haven't had mineral levels tested, Jimmylegs.
From Sarah's link-
Sunlight on our skin is now thought to be the main 'source' of vitamin D. Whilst a little is found in dairy, the major source is fish liver oils and particularly cod liver oil. Plants contain very little vitamin D. Kidney or liver disease (and alcohol) depress vitamin D levels, as do cholesterol-lowering drugs (e.g. statins), mineral oils, anticonvulsants and toxic chemicals in the environment (e.g. smog). Cadmium blocks vitamin D production whilst pantothenic acid helps make it. Night shift workers have lowered blood levels of vitamin D. Heavily tanned, or black people cannot make vitamin D through the process of sunlight in their skin.
interesting,
AC
Re: Study questions Vit D intake
I'm not sure what happened though the link is fixed now. Thanks for pointing it out.gwa wrote:I assume that you posted the wrong link. If not, what does the link have to do with Vit D?
NHE
to all vitamin D supplementers
i've been up on the calcium part of this, but have had trouble coming up with the magnesium numbers.
if you did not already know the following, we have Nick to thank - I had been rummaging around unsuccessfully. Nick answered my PM right away and mentioned "embry", which i added to my search terms and found this:
http://www.msrc.co.uk/index.cfm?fuseact ... &pageid=39
if you did not already know the following, we have Nick to thank - I had been rummaging around unsuccessfully. Nick answered my PM right away and mentioned "embry", which i added to my search terms and found this:
http://www.msrc.co.uk/index.cfm?fuseact ... &pageid=39
when i have more time i will look into that statement and try to discover the sources.It is essential that, while supplementing with vitamin D3(cholecalciferol), you also supplement with 1200mg essential calcium and 600-1200mg magnesium, to prevent osteoporosis.