Dramtic decrease in EDSS with Liver Transplant ? Why ?
What if there is some sort of viral or bacterial infiltration of the liver that creates some soft of MS like syndrome?
What really strikes me is the fact that I have had elevated liver enzymes for a while, before I ever took Ifn-b. It came up in a blood test a long time ago when I had severe abdominal pain. They thought I might have hepatitis, but it turned out that I didn't. I remember the ultrasound of my liver then and it was nice and smooth.
Then, when I was in the hospital with my first real relapse, they mixed up some paper work and had another ultrasound of my liver done. I thought that was strange. But, it turned out that now I have a fatty liver. I saw it in that image then as well and it was rough looking and pitted, it didn't look smooth like it did before.
After that while i was still in the hostpital, they checked my hepatic levels again and all was fine. A year after that, they checked again and enzymes were once again elevated.
Anyway, just thinking out loud.
Brock
What really strikes me is the fact that I have had elevated liver enzymes for a while, before I ever took Ifn-b. It came up in a blood test a long time ago when I had severe abdominal pain. They thought I might have hepatitis, but it turned out that I didn't. I remember the ultrasound of my liver then and it was nice and smooth.
Then, when I was in the hospital with my first real relapse, they mixed up some paper work and had another ultrasound of my liver done. I thought that was strange. But, it turned out that now I have a fatty liver. I saw it in that image then as well and it was rough looking and pitted, it didn't look smooth like it did before.
After that while i was still in the hostpital, they checked my hepatic levels again and all was fine. A year after that, they checked again and enzymes were once again elevated.
Anyway, just thinking out loud.
Brock
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I eat fairly healthy, and don't drink alchohol very often at all. I don't smoke, never have. I don't exercise as much as I should, and probably don't drink as much water as I should either.
before I was diagnosed with MS though, I did drink A LOT of diet soda. I hardly drink any now, but I do have it from time to time.
I hope that answers your questions..
before I was diagnosed with MS though, I did drink A LOT of diet soda. I hardly drink any now, but I do have it from time to time.
I hope that answers your questions..
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Hey Brock...
you are not alone. Many MSers have high liver enzymes and fatty liver for no "apparent" reason. I put together a whole thread on this topic, since I became interested in the liver's implication in MS when my husband was dx. He was told by his neuro he drank too much...and he rarely has a glass of wine. His liver enzymes were thru the roof. I knew something was amiss, because he looked jaundiced as well.
Here's the thread...read up and ask any questions you might have-
http://www.thisisms.com/ftopict-5595-liver.html+enzyme
AC
you are not alone. Many MSers have high liver enzymes and fatty liver for no "apparent" reason. I put together a whole thread on this topic, since I became interested in the liver's implication in MS when my husband was dx. He was told by his neuro he drank too much...and he rarely has a glass of wine. His liver enzymes were thru the roof. I knew something was amiss, because he looked jaundiced as well.
Here's the thread...read up and ask any questions you might have-
http://www.thisisms.com/ftopict-5595-liver.html+enzyme
AC
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
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I understand you only said "many" and not all, but I actually have a "bullet proof" liver. I am on the highest dose of Lipitor, and have tried many other liver toxic medications, but my readings (thankfully) are always with the normal range, or only marginally outside on 1 or two; nothing that has concerned my doc.cheerleader wrote:Many MSers have high liver enzymes and fatty liver for no "apparent" reason.
By the way, what is the measure for a "fatty liver"?
Haven't you posted lately that you don't have any symptoms? If so, maybe your "MS" was really caused by the aspertame in diet sodas. Symptoms go away when a person stops drinking the diet colas and eating diet foods.viper498 wrote:
before I was diagnosed with MS though, I did drink A LOT of diet soda. I hardly drink any now, but I do have it from time to time.
Just a thought.
gwa
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If the liver enzymes are high and do not resolve in a couple of weeks, docs will do an ultrasound or MRI or biopsy. If the liver is inflamed, or has fatty deposits, ya got a fatty liver. Jeff never had the ultrasound, since his enzymes resolved on their own. Congrats on your slim and trim, liver, Cure!CureOrBust wrote: By the way, what is the measure for a "fatty liver"?
AC
Husband dx RRMS 3/07
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
dx dual jugular vein stenosis (CCSVI) 4/09
http://ccsviinms.blogspot.com
Since interferon use can cause liver failure, I think there are a few more people out there who have also had liver transplants and have MS - I wonder how they're doing. Wouldn't that be a kicker if there are people who actually suffered liver failure BECAUSE of MS treatment and then went on to experience a remission due to liver transplant?
I'd personally think the remissions would be more related to the immunosuppressants since we're now using potent anti-rejection transplant immunosuppressants in the treatment of MS. That just seems to be the more logical connection rather than any change due to the new liver itself.
I'd personally think the remissions would be more related to the immunosuppressants since we're now using potent anti-rejection transplant immunosuppressants in the treatment of MS. That just seems to be the more logical connection rather than any change due to the new liver itself.