Hormone Replacement

[jimmylegs]

Interrelationship of magnesium and estrogen in cardiovascular and bone disorders, eclampsia, migraine and premenstrual syndrome (1993)
https://pubmed.ncbi.nlm.nih.gov/8409107/

[Jaded]

Ah pleased to hear it! Sorry it's been roasting here.....yikes

[jimmylegs]

I'd heard! Hope folks have come thru all right. My entire Canadian family is over your way just now
In other news, had an appointment Monday. Not a complete win, but I think a good step in prep for this Friday. Otherwise, this week is absolute crap - need to turn things around if I can!

[Jaded]

Good luck with that - of course you can turn things around. Try the Amy Cuddy postures!

Must be a system shock for your Canadian family. We had rain today - just a little but what a relief - and it's slightly cooler thankfully. Phew.

[jimmylegs]

lol i had to look up Amy Cuddy hahaha
yeah this week just feels like straight up relapse. #4 by my count. boo! i liked MS better before these started.
i just noticed this abstract and thought of you

A Personal Prospective on Testosterone Therapy in Women—What We Know in 2022
https://www.mdpi.com/2075-4426/12/8/1194/htm

some choice tidbits in there

hope all was reasonably well today, on your side of the pond!

[jimmylegs]

Seems like I may have found the right specialist!! So excited for this experiment.

[Jaded]

Ah good to hear you have found that right specialist! How did it go?

Interesting paper - thanks. It touched on something I forgot which we ought to flag here - that HRT helps prevent Alzheimer's - something I heard in a podcast. Note that this is a recent discovery. I shall find the link and come back here. The study was prompted by higher rates of Alzheimer's in women.

[jimmylegs]

it went really well. expensive, and i'm still a bit skeptical of some aspects, but i am thrilled that she will consider stepping outside the box, and will entertain the idea of joining me on this latest learning curve.
i'll be looking forward to seeing that research link when you find it!

[Jaded]

Ah good news!

She's a neuroscientist - Dr Lisa Mosconi

One of the published papers on her website - can send you the podcast too. There are others (https://www.lisamosconi.com/)

https://pubmed.ncbi.nlm.nih.gov/34108509/

[jimmylegs]

thx, will check it out!

[jimmylegs]

so i did have a look, but need to go back and read again.

in other news, the HT ball is really rolling now. tomorrow is next-level go time!

[jimmylegs]

it 'begins'!

[jimmylegs]

Menopausal symptoms and hormone therapy in women with multiple sclerosis: A baseline-controlled study
https://www.sciencedirect.com/science/a ... 482200606X
"Improvements in vasomotor, depressive, and insomnia symptoms observed during one year of MHT are encouraging and suggest that larger placebo-controlled studies of MHT in women with MS are warranted."

[Jaded]

Hi JL

So here I am having picked up that earlier in this thread you mentioned being on a thyroid hormone. Sorry I didn't see that before

I did a search and found this thread again because some blood tests done this week came back ok except my cholesterol was above 5. But on looking closer I see my T4 has been falling and TSH is high. Both are still within the range but it would explain the extreme tiredness I am feeling, and also the cold.

How is your treatment going? Has it helped you?
J

[jimmylegs]

Hi Jaded!

i have a few hormone prescriptions going now. it's hard to say conclusively, but i think i feel better in a few ways but it's harder to see progress in others. please forgive any repetition in the following.

one of the earliest was the armour desiccated thyroid 30mg/d. i was surprised that new specialist had ordered the test, not having had any particular symptoms that pointed that direction. when i first saw my results all were normal, but tending to hypo. my TSH looked a little above ideal with T3 and T4 a little below.
after a couple of months on the rx, everything was on track. my numbers actually looked a smidge 'hyper' to my layperson's eye, but the specialist was pleased and did not adjust the dosage. the T4 was up to 13 pmol/L, and the TSH down just below 1 mIU/L.
my next follow up appt is in january. so far, i have no complaints about desiccated thyroid.

For other hormones it hasn't been as easy to move the needle with the lab results. i'm being as diligent as i can, trying to remain patient, and hoping for good things!

most recently, I tried an OTC sublingual melatonin spray for the first time. subjectively, 1mg seemed to work like a charm here's hoping for at least some more good subjective news with everything else!