Updated recommendations to minimize the risk of the rare brain infection PML with Tecfidera.
http://www.ema.europa.eu/ema/index.jsp? ... 058004d5c1
Search found 163 matches
- Fri Nov 27, 2015 2:46 am
- Forum: Tecfidera (BG-12, Dimethyl fumarate)
- Topic: Have Your doctor test lymphocyte count
- Replies: 3
- Views: 5898
- Sat Apr 11, 2015 12:05 am
- Forum: General Discussion
- Topic: Seizure of epilepsy
- Replies: 0
- Views: 1320
Seizure of epilepsy
Have any of you had a single seizure of epilepsy? I have been on Gilenya for one year and just came back home from hospital emergency department (with a broken head and five stitchese...) :( I had Tysabri before G (for one and half year) but left it since my JCV antibody index have reached 3,8 and t...
- Wed May 23, 2012 7:36 am
- Forum: Tysabri (Antegren, Natalizumab)
- Topic: 242 PML cases and 52 deaths - May 2012
- Replies: 9
- Views: 8117
242 PML cases and 52 deaths - May 2012
Biogen Idec confirmed 10 new cases of PML (0505 2012). The total number of PML cases among the Tysabri users rises to 242 and the total number of deaths increased at 52 (three other patients died of PML). PML patients mortality is currently about 21 percent.
- Wed Mar 14, 2012 1:07 pm
- Forum: General Discussion
- Topic: Copaxone and radioactive iodine - does if fit together?
- Replies: 1
- Views: 1493
Copaxone and radioactive iodine - does if fit together?
Is here anyone who experienced cancer in addition to MS? I am wonder if the tests associated with one shot of radioactive iodine (two weeks at the hospital are a must) can be done while someone is on immunomodulatory drugs? Does anyone know if the administration of Copaxone should be interrupted for...
- Sun Feb 19, 2012 4:29 am
- Forum: Tysabri (Antegren, Natalizumab)
- Topic: Febuary 1, 2012: 207 PML cases on natalizumab (44 deaths)
- Replies: 2
- Views: 3514
Febuary 1, 2012: 207 PML cases on natalizumab (44 deaths)
Since January 2012 (as of Febuary 1), there have been six more PML patients and two more deaths.
It means 207 confirmed cases of PML and 44 of them have died (21%).
There have been about 98.000 MS patients on natalizumab worldwide.
It means 207 confirmed cases of PML and 44 of them have died (21%).

There have been about 98.000 MS patients on natalizumab worldwide.
- Sat Jan 21, 2012 3:01 pm
- Forum: Tysabri (Antegren, Natalizumab)
- Topic: 159 cases of PML with 29 deaths for Tysabri MS patients
- Replies: 29
- Views: 14506
Re: 159 cases of PML with 29 deaths for Tysabri MS patients
3 more patients with PML have died (total 42)...
- Fri Dec 30, 2011 4:24 pm
- Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
- Topic: tumor
- Replies: 2
- Views: 1442
Re: tumor
The tumor was found incidentally during a routine ultrasound control after the procedure, all the laboratory tests were (and still are) all right as well as the clinical condition of the patient. This creates the impression to thoroughly examine the thyroid before procedure, to avoid what happened t...
- Fri Dec 30, 2011 4:10 pm
- Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
- Topic: tumor after baloon angioplasty...
- Replies: 2
- Views: 1596
Re: tumor after baloon angioplasty...
...This could lead to an unhealthy state in the thyroid, which would be relieved when CCSVI venoplasty is performed. That was exactly my reasoning - whether improved jugular vein flow may have contributed to the fact that the tumor began to be better nourished and therefore had ideal conditions for...
- Fri Dec 30, 2011 4:07 pm
- Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
- Topic: tumor
- Replies: 2
- Views: 1442
tumor
That was exactly my reasoning - whether improved jugular vein flow may have contributed to the fact that the tumor began to be better nourished and therefore had ideal conditions for growth. Do the patients after balloon angioplasty experience any problems with their thyroid?
- Fri Dec 30, 2011 11:07 am
- Forum: Chronic Cerebrospinal Venous Insufficiency (CCSVI)
- Topic: tumor after baloon angioplasty...
- Replies: 2
- Views: 1596
tumor after baloon angioplasty...
A friend of mine was detected CCSVI, followed by balloon angioplasty in November 2010 and few month later (in May 2011) doctor found a tumor of the thyroid gland. It was found by chance just because of jugular vein´s ultrasound. Unfortunately, it is a malignant tumor. Could improvement of the blood ...
- Fri Dec 16, 2011 11:02 am
- Forum: Tysabri (Antegren, Natalizumab)
- Topic: 159 cases of PML with 29 deaths for Tysabri MS patients
- Replies: 29
- Views: 14506
Re: 159 cases of PML with 29 deaths for Tysabri MS patients
Yes, one more death increased the number up to 39...HarryZ wrote:...Don't know if there are any more deaths included in this new number.
- Sun Nov 20, 2011 1:28 pm
- Forum: Tysabri (Antegren, Natalizumab)
- Topic: 159 cases of PML with 29 deaths for Tysabri MS patients
- Replies: 29
- Views: 14506
Re: 159 cases of PML with 29 deaths for Tysabri MS patients
11 new cases of PML and 5 more deaths (since the beginning of October 2011).HarryZ wrote:Latest figures show the number of PML cases has risen to 181. It isn't known if any more deaths are included in the recent increase.
Harry
Total November numbers: 181 PML patients and 38 PML deaths...
- Sun Oct 30, 2011 10:13 am
- Forum: Copaxone
- Topic: Synthon’s Glatiramer Acetate (GTR) in RRMS
- Replies: 0
- Views: 2993
Synthon’s Glatiramer Acetate (GTR) in RRMS
Has anyone heard about this:
Synthon’s Glatiramer Acetate (GTR) in RRMS?
What is the difference comparing it to well known glatiramer acetate?
Synthon’s Glatiramer Acetate (GTR) in RRMS?
What is the difference comparing it to well known glatiramer acetate?
- Fri Oct 28, 2011 9:33 am
- Forum: Tysabri (Antegren, Natalizumab)
- Topic: 33 deaths due to PML
- Replies: 5
- Views: 3217
Re: 33 deaths due to PML
Does anyone know how many total number of patients on Tysabri as of Oct 4? Biogen Idec announced today: "...as of the end of September 2011, we estimate that approximately 63,500 patients were on commercial and clinical TYSABRI therapy worldwide, and that cumulatively approximately 92,200 pati...
- Sat Oct 15, 2011 11:16 am
- Forum: Tysabri (Antegren, Natalizumab)
- Topic: 33 deaths due to PML
- Replies: 5
- Views: 3217
33 deaths due to PML
MS patients on Tysabri: 170 PML cases, 33 deaths already (as of 4-th of October 2011). "...as of the end of September 2011 approximately 63,500 patients were on commercial and clinical TYSABRI therapy worldwide. And that cumulatively approximately 92,200 patients have ever been treated with TYS...