A Postural Connection With MS? Please Answer Poll Questions

[AndrewKFletcher]

BUMP

Need 100 votes at least, if you havent voted please do and help complete this poll

[1eye]

I heard tell that the CNS does have a pump, called tha Sodium Pump.

[AndrewKFletcher]

Acta Neurochir Suppl. 2005;95:177-81.
MRI study of cerebral blood flow and CSF flow dynamics in an upright posture: the effect of posture on the intracranial compliance and pressure.

Alperin N, Hushek SG, Lee SH, Sivaramakrishnan A, Lichtor T.

Department of Radiology, The University of Illinois at Chicago, 60612, USA. alperin@uic.edu
Abstract

Postural related changes in cerebral hemodynamics and hydrodynamics were studied using Magnetic Resonance Imaging (MRI) measurements of cerebral blood flow and cerebrospinal fluid (CSF) flow dynamics. Ten healthy volunteers (mean age 29 +/- 7) were studied in supine and upright (sitting) postures. A Cine phase-contrast MRI technique was used to image the pulsatile blood flow to the brain, the venous outflow through the internal jugular, epidural, and vertebral veins, and the bi-directional CSF flow between the cranium and the spinal canal. Previously published analyses were applied to calculate and compare total cerebral blood flow (TCBF), intracranial compliance and pressure in both postures. A lower (12%) mean TCBF was measured in the upright position compared to supine position. A considerable smaller amount of CSF flow between the cranium and the spinal canal (58%), a much larger intracranial compliance (a 2.8-fold increase), and a corresponding decrease in the MRI-derived ICP were also measured in the sitting position. These changes suggest that the increased cerebrovascular and intracranial compliances in the upright posture are primarily due to reduced amounts of blood and CSF residing in their respective intracranial compartments in the upright position. This work demonstrates the ability to quantify neurophysiologic parameters associated with regulation of cerebral hemodynamics and hydrodynamics from dynamic MR imaging of blood and CSF flows.

PMID: 16463846 [PubMed - indexed for MEDLINE]

[Algis]

I am convinced that (IF) my MS is vascular in origin; then it is due to postural behavior.

I work on computer since 30 years and finally almost roll down to the keyboard

[AndrewKFletcher]

In order to complete this survey, we need 6 more votes on the Postural Poll


So if you have not already done so please add your vote and if possible add a comment to let us know a little more about your reasoning for the vote, whatever it is.

Andrew

[AndrewKFletcher]

Hi Algis

Thought you might like this:

Phil Collins Overcomes Challenge of Drumming After Spinal Cord Injury

Former drummer and later front man of the legendary band Genesis, Phil Collins has recently undergone spinal surgery on the vertebrae in his neck after years of drumming in a poor posture left him with a spinal cord injury and nerve damage. Collins told Rolling Stone: “My vertebrae has been crushing my spinal cord because of the position I drum in. It comes from years of playing. I can’t even hold the sticks properly without it being painful.” More on Phil Collins:-----
http://www.andrewkfletcher.com/index.ph ... id=30#p674

[Algis]

Thank you Andrew; but it does not surprise me at all. A world-known violinist that I meet sometimes has the same (well; similar) problem after 40 years of intense practice. She cant play any more than few minutes without having 'eye flashes' and 'numb arms and fingers'.

She is seeing a chiropractor with 'very' mixed results.

Cheers!

[CureOrBust]

You forgot the option of "none of the above" in the poll

[AndrewKFletcher]

Hi Cure

Hard to fathom out what someone would be doing at the time of their downturn if not either standing, sitting or laying down. Spose they could be sky diving, or swimming

[AndrewKFletcher]

A big thank you too all the people who voted on the MS posture survey 100 votes is A fantastic response from the people at Thisisms and from my friends on Facebook and at the Multiple Sclerosis Resource Centre. This has proved to be a very interesting POLL showing a clear connection with sitting and sleeping postion. The Survey will remain open so if you have not yet voted lets make it 200 votes. I will be forwarding the results to the Multiple Sclerosis Resource Centre in Essex and to Professor Zamboni, Dr Claude Francheshi, Dr Franz Schelling and others to learn how they view the results.

Some very interesting patterns indeed.

Andrew

[CureOrBust]

Hard to fathom out what someone would be doing at the time of their downturn if not either standing, sitting or laying down. Spose they could be sky diving, or swimming

I ccant speak for others, but a relapse / downturn is not a bolt of thunder, it occurs over time, over which you may end up doing all of the above; including "sky diving, or swimming ".

[AndrewKFletcher]

Email: Permission Obtained From Dr Schelling to share
RE: Posture Survey conducted on Thisisms Forum reached 100 vote target‏
From: Dr. Franz Schelling
Sent: 19 June 2010 08:16:04
To: 'Andrew K Fletcher'

Dear Andrew,



The discrepancy between 1% deteriorations noticed at night while trying to get out of bed and 17% upon rising from bed as well as 18% upon waking in the morning appears remarkable.

In regard of the underlying haemo- and CSF-dynamic events, Alperin’s study fails to take into account that it is respiratory and other other bodily movements and exertions which alter intra- cerebral and –spinal fluid dynamics for more abruptly and intensely than arterial pulsations.



What I would yet primarily be interested to learn more about are the effects of raising the MS patients’ beds at different angles – and the dependence of these effects upon the presence of different forms of stenosis of, on the one hand, lesion-related and, on the other, not lesion related venous drainage systems of the brain.



Sincerely,

Franz

[scorpion]

You forgot the option of "none of the above" in the poll

I agree Cure that relapses are generally gradual. I would have to answer none of the above. My relapses occurred slowly. My episode of ON occured
while on the treadmill at a gym. I don't see that as one of the options.

[AndrewKFletcher]

You forgot the option of "none of the above" in the poll

I agree Cure that relapses are generally gradual. I would have to answer none of the above. My relapses occurred slowly. My episode of ON occured
while on the treadmill at a gym. I don't see that as one of the options.

Treadmill is walking

[AndrewKFletcher]

BUMP