herbals

[jackD]

with some VINPOCETINE 10 mg treee times a day. It helps the voiding problem and it cures MS, makes you very smart and cures several other minor diseases.

Sorry but this just sounds too like a snake oil routine to me.
Cures MS!???


If anyone else would like to reply re. Green Tea and Bladder issues I'd very much like to hear your experiences.
Thanks

[/quote]

Here is HOW Vinpocetine and other Phosphodiesterase inhibitors help protect the nervous system. Of course you MUST know HOW MS progresses in order to understand this.

jackD

Mult Scler. 1999 Apr;5(2):126-33.

Effects of phosphodiesterase inhibitors on cytokine production by microglia.

Yoshikawa M, Suzumura A, Tamaru T, Takayanagi T, Sawada M.

Department of Neurology, Nara Medical University, Kashihara, Japan.

Type III and IV phosphodiesterase inhibitors (PDEIs) have recently been shown to suppress the production of TNF-alpha in several types of cells.

In the present study, we have shown that all the types of PDEIs, from type I- to V-specific and non-specific, suppress the production of TNF-alpha by mouse microglia stimulated with lipopolysaccharide (LPS) in a dose-dependent manner.

Certain combinations of three different types of PDEIs synergistically suppressed TNF-alpha production by microglia at a very low concentration (1 microM).

Since some PDEIs reportedly pass through the blood-brain barrier (BBB), the combination of three PDEIs may be worth trying in neurological diseases, such as multiple sclerosis and HIV-related neurological diseases in which TNF-alpha may play a critical role.

Some PDEIs also suppressed interleukin-I (IL-I) and IL-6 production by mouse microglia stimulated with LPS.

In contrast, the production of IL-10, which is known to be an inhibitory cytokine, was upregulated by certain PDEIs.

The suppression of TNF-alpha and induction of IL-10 were confirmed at the mRNA level by RT-PCR. PDEIs may be useful anti-inflammatory agents by downregulating inflammatory cytokines and upregulating inhibitory cytokines in the central nervous system. (CNS).

PMID: 10335522 [PubMed - indexed for MEDLINE]

[zinamaria]

JackD I had to smile when I read how you treat yourself to your bit of chocolate and tea!! Me too, but I have upped the anti to 90% dark, and also have found a superb 100% bar. I too only have the smallest amount per day. We have also found a bar (I do not do sugar and use stevia for all) and now this is raw chocolate, (full of antioxidents) sweetened with xylitol. It is delicious. Again, just a few squares in a day.
Now that I have exposed my chocoholic tendencies, what about the saturated fat in cocoa? This is my greatest concern, however my sat fat daily is almost nil...

Any comments?

Peace
Zina

[Wonderfulworld]

No Jimmylegs haven't ever tried EGCG. I will have a look in the healthshops and see if it works without the knock-on effect on the bladder.
I am not 100% sure that green tea being a diuretic is the whole reason for the problem. I drink 2 x large mugs of strong coffee in the morning, maybe 3 - but yet it doesn't effect my bladder that evening. I have cut it out in the past and there is no effect either positive or negative on voiding that evening. Yet the green tea capsules, even taken that morning, do effect my bladder very adversely.

JackD -

Maybe a big properly done study will find a 100% REDUCTION rate.

Yes but maybe in won't!

You might be onto something in the decaffeinated green tea, will check it out.

[jimmylegs]

hi ww, i suspect, without knowing for sure, that green tea capsules (being that much more concentrated than mugs of green tea) may pack a stronger diuretic punch than liquid coffee, however strong. just my suspicion.

[Selmahope]

http://www.longvida.com/index.php?gclid ... DQodzBnaNA

Has anyone tried this brand of curcumin- your link for what you are taking did not work.

Do you think you could just put a teaspoon of tumeric in hot water and have the same or better effect with whole herb?

[goonasi]

I have been taking Source Naturals curcumin with great effect. It started to reduce the numbness in my legs and feet and I felt kind of human again ! I live in England and as it is relatively cheaper this way I purchased the turmeric product via iHerb,U.S.A. I stated to take 1 a day nothing was happening so upped it to 2 a day and then to 3 a day spread out with my breakfast, lunch and dinner.

I have posted before enquiring about supplements which you were all a great help and I started to see some great changes for the good and then suddenly it came to a halt. The only thing that changed was I let the Source Naturals Curcumin run low and then obviously in time ran out. Being clever I re-ordered some again but changed brand to Doctors best c3 complex with bioperine, did my reading on it, albeit nice and expensive over here, I bought some and BLIMEY ! the gastrointestinal irritation warning was an understatement so I went back to iHerb and instead of buying Source Naturals Curcumin product I was again smart and changed brand to Life Extensions Super Bio-Curcumin after to some impressive reports/reading and BLIMEY ! the gastrointestinal irritation warning was again an understatement so I went back to iHerb and reordered my trust worthy Source Naturals Curcumin which now has the same effects as the previous two products. I am trying not to be crude when I say this but they all go straight through me now and scared to move so to speak in case of an accident ! I cannot understand why this is now happening as it seemed to work before and nothing has changed. When Iam brave I go back and dabble with the tumeric the numbness in my feet and legs do start to move its just the awful side effects I cant cope with. I have tried different times to take the tumeric but it has the same effect.

Any advise would be extremely grateful.

[lyndacarol]

Once again I have been watching the Dr. Oz TV program. Today he briefly mentioned that ginkgo biloba has been found to improve vertigo and no one knows the reason why. He did suggest that ginkgo biloba affected the circulation.

Below is the link to the show's video dealing with this topic, 4 minutes into it is the mention of the effect on the ears and vertigo:

http://www.doctoroz.com/videos/does-it- ... kgo-biloba

I thought others might find it interesting, too.

[LR1234]

Cool, I will give it a go!! x

[Alexandra]

Did anyone try aloe vera and goji berry for MS?
I did a bit of reading about aloe vera and it seems it has MMP9 reduction properties and people say pain also disappears. would be interesting to see if others had any results on it. my concern is that these plants also boost the immune system

http://iadr.confex.com/iadr/sea05/preli ... _69882.htm

[Alexandra]

I am monitored by both neurologists and immunologists as I do believe this is an immunity disorder. My immunologist also recommended me this noni juice. Anyone else tried it?

[Courts]

Thanks for posting this gibbledygook. I've been making my own hot chocolates with a teaspoon of pure cacao powder, I also eat alot of chololate.

I'm gonna stop the cacao and try to avoid chocolate and see if that helps my current relapse. I've also read that cacao is a diuretic and I've recently been experiencing bladder problems for the first time ever (hugely scary and upsetting for me) so I wonder if the cacao has made that worse also.

I'll see how it goes and post my results

[1hotmama]

Ginko biloba is a blood thinner along with an herb that helps brain function and nerve repair. Vertigo is a symptom that I have rarely but I have noticed a big difference in fatigue. I started taking two capsules daily of ginko, then increased to four and I now wake up easier and can stay awake longer. I no longer take naps for 32 hours and all I changed was increasing my ginko intake. My doctor says that everyone should take ginko for "brain health". I think of it as a maintenance nutrient just like vitamin D and calcium.

[harpgirl]

I too would like to know if I can mix in water. I ordered powdered tumeric over the internet to use in foods. Have lots and wonder if it will benefit me to ingest via water.

[jackD]

No!

Curcumin's low systemic bioavailability after oral dosing gives it a very poor therapeutic value even if taken in huge oral amounts.

You need to do something to enhance absorption. Read previous postings about this in this thread.

JackD

[jackD]

Since we are sick humans maybe we absorb more.

jackD

Planta Med. 1998 May;64(4):353-6.

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers.

Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS.

Department of Pharmacology, St. John's Medical College, Bangalore, India.

Abstract
The medicinal properties of curcumin obtained from Curcuma longa L. cannot be utilised because of poor bioavailability due to its rapid metabolism in the liver and intestinal wall.

In this study, the effect of combining piperine, a known inhibitor of hepatic and intestinal glucuronidation, was evaluated on the bioavailability of curcumin in rats and healthy human volunteers.

When curcumin was given alone, in the dose 2 g/kg to rats, moderate serum concentrations were achieved over a period of 4 h. Concomitant administration of piperine 20 mg/kg increased the serum concentration of curcumin for a short period of 1-2 h post drug. Time to maximum was significantly increased (P < 0.02) while elimination half life and clearance significantly decreased (P < 0.02), and the bioavailability was increased by 154%.

On the other hand in humans after a dose of 2 g curcumin alone, serum levels were either undetectable or very low.

Concomitant administration of piperine 20 mg produced much higher concentrations from 0.25 to 1 h post drug (P < 0.01 at 0.25 and 0.5 h; P < 0.001 at 1 h), the increase in bioavailability was 2000%.

The study shows that in the dosages used, piperine enhances the serum concentration, extent of absorption and bioavailability of curcumin in both rats and humans with no adverse effects.

PMID: 9619120 [PubMed - indexed for MEDLINE]