T Cell Vaccination

A board to discuss future MS therapies in early stage (Phase I or II) trials.
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tmcdaniel
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T Cell Vaccination

Post by tmcdaniel »

An article worth reading about
T Cell Vaccination.

http://www.bcm.edu/neurology/msrl/t_cel ... ation.html[/url]
Lyon
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Post by Lyon »

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Last edited by Lyon on Tue Jun 21, 2011 2:40 pm, edited 1 time in total.
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Daisy3
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Post by Daisy3 »

Would love Loobie to respond:-)
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patientx
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Post by patientx »

It looks like many of the references in that link are from the mid-90's, early 2000's. Does anyone know if this was this the forerunner of Opexa and Tovaxin, or was it a separate line of research into T-cell vaccination?
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Post by Lyon »

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Last edited by Lyon on Tue Jun 21, 2011 2:41 pm, edited 1 time in total.
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patientx
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Post by patientx »

Lyon wrote:It's a forerunner of Tovaxin because it regards the same Dr Zhang who developed Tovaxin
Thanks.

I've often wondered about the T-cell vaccination approach. Given the research showing that there's more going on beside just de-myelination (i.e. nerve cell death), and that B cells may somehow be involved, is targeting myelin reactive T cells enough? Especially considering that treatments like Campath, which target both T cells and B cells, show good results. I wonder if the researchers investigting the T-cell vaccination considered this, or if they just focused on the de-myelination aspect of MS.
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