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Annual Meeting – Italy
By Mark Godley | Published: November 15, 2010
ISNVD Annual Meeting
Ferrara, March 13, 2011 Italy
Vascular Diseases Center University of Ferrara – corso Giovecca 203
Bologna, March 14-15, 2011 Italy
CNR National Research Council of Bologna – via Gobetti 101
Major topics covered:
•Ultrasound and MR imaging in treatment planning
•The role of iron in MS and neurodegenerative disease
•Perfusion deficits and hypoxia and possible relationships to CCSVI
•New evidence of CCSVI in animal models
•Related vascular problems: venous embriology, idiopathic intracranial hypertension, normotensive hydrocephalus, carotid surgery in stroke
•CCSVI treatment: procedure and neurological outcomes
•Genetic studies
•Plethysmography
•Flow dynamics: modeling the cerebral venous system
Ok, I want to know about the new evidence of CCSVI in animal models. We also have not talked much about those related vascular problems: anyone know what venous embriology or normotensive hydrocephalus look like? I also see plethysmography on the list, this is what Dr. Zamboni is investigating.
Cece wrote:
Ok, I want to know about the new evidence of CCSVI in animal models. We also have not talked much about those related vascular problems: anyone know what venous embriology or normotensive hydrocephalus look like? I also see plethysmography on the list, this is what Dr. Zamboni is investigating.
Pretty great stuff, huh, Cece? Hoping to go to the next meeting in March. The animal models have been promised on here for a while, and are finally being written up and ready for publication. Can't give away any more.
Normal pressure hydrocephalus was suggested by neurologist Dr. Eliot Frohman as a correlation to CCSVI in Bologna last year...I wrote about it on here:
I have seen this happen in “normal pressure hydrocephalus- (NPH) Where there is a loss of gait, cognitive and bladder issues and the lesions disappear because the expanded ventricle swallows the lesion. I have shunted the brains of NPH patients, and they showed remarkable improvements. Again, the enlargement of the third ventricle precedes the changes.
As I said in another thread ... The CCSVI wave is building and about to come ashore with a thundering crash (and there are many many more waves behind it) ...
This is GREAT stuff ... I can't wait until it's all out there (and see how they try to argue against it then).
Keep up the great work cheer (and Cece) ... the CCSVI Alliance is fantastic.
a bit on third ventricular enlargement in MS, I remember this stuff from preCCSVI days, when it was a mystery:
We demonstrated that progressive brain atrophy in MS
patients can be assessed reliably by measuring third
ventricular diameter with transcranial sonography
(TCS) within a 1 year follow up. Moreover, clinical disability
correlated significantly with third ventricular diameter
at all time points.Higher EDSS values after a two
year follow-up were found to be associated with an already
enlarged size of the third ventricle at study entry.
Can't wait for more on the animal model of CCSVI. What was Dr. Zamboni's line last fall? "I am not a mouse doctor"? He didn't have to be, there are other doctors who can do that, as all the eae mice can attest.
Cece wrote:a bit on third ventricular enlargement in MS, I remember this stuff from preCCSVI days, when it was a mystery:
We demonstrated that progressive brain atrophy in MS
patients can be assessed reliably by measuring third
ventricular diameter with transcranial sonography
(TCS) within a 1 year follow up. Moreover, clinical disability
correlated significantly with third ventricular diameter
at all time points.Higher EDSS values after a two
year follow-up were found to be associated with an already
enlarged size of the third ventricle at study entry.
Right! Dr. Frohman was the one who put that together...don't even think it was on the other doctors' radar in Bologna, since the vascular doctors were not MS specialists. He mentioned the third ventricle and CCSVI, and the lights went on. This is why it is SO important to have neurologists and vascular doctors cooperating. Perfect example.
Can't wait for more on the animal model of CCSVI. What was Dr. Zamboni's line last fall? "I am not a mouse doctor"? He didn't have to be, there are other doctors who can do that, as all the eae mice can attest.
exactly, Cece. There are doctors who do these types of experiments with mice, and they were very interested in the model of CCSVI. Those papers can't be published soon enough
He didn't have to be, there are other doctors who can do that, as all the eae mice can attest.