hi ww
that's great that your sleep has improved some!
i found this link on neurogenic bladder and sure enough the pharma approach is to treat the spasm.
http://www.healthtree.com/articles/blad ... eurogenic/
As for medication, doctors usually prescribe:
*anticholinergic drugs (drugs that inhibit the communication of certain nerve cells)
*antispasmodics (drugs that prevent certain muscles from contracting)
*muscle relaxants
i notice they don't mention magnesium specifically.. not sure if there are any studies to find out whether ms patients are deficient in pharma antispasmodics or muscle relaxants, but i did find this:
http://www.sid.ir/en/VEWSSID/J_pdf/118620080207.pdf
Assessment of Serum Magnesium, Copper, and Zinc Levels in Multiple Sclerosis (MS) Patients
Mean serum levels of magnesium, copper, and zinc in MS patients were significantly lower than control group (1.87 ± 0.37 , 110.7 ± 19.5 , 85.4 ± 13.5 VS. 2.22 ± 0.24 , 133.7 ± 13.4, 110 ± 8.3 respectively) (P< 0.001).
here's the units conversion, hopefully displayed in a more readable fashion (c = control):
magnesium
mg ms 1.87 mg/dl x0.411= 0.77 mmol/L
mg c 2.22 mg/dl x0.411= 0.91 mmol/L
copper
cu ms 110.7 µg/dL x0.157=
17.4 µmoI/L
cu c 133.7 µg/dL x0.157=
21.0 µmoI/L
zinc
zn ms 85.4 µg/dL x0.153=
13.1 µmoI/L
zn c 110 µg/dL x0.153=
16.8 µmoI/L
so just looking magnesium, usually the
reference range for magnesium is given as
0.70-1.10 mmol/L but in the research
0.90 mmol/L has been identified as a
minimum.
this tells us two things. one, if you as an ms patient go for a serum mg test, you will fall inside the reference range and be told it's all good.
two, the research i usually go to as a source for minimum status is pretty bang on compared to the above finding of 0.91 mmol/L in controls
here's that research re mag status (2004):
http://www.jacn.org/cgi/content/full/23/6/730S
In patients with Mg serum values lower than 0.9 mmol/l Mg, magnesium supplementation is recommended; for patients with values lower than 0.8 mmol/l, starting Mg supplementation is necessary. We recommend that a Mg serum value of 0.9 mmol/l Mg be considered as the lower reference limit, in evaluating symptoms or diseases suspected as being associated with Mg deficiency. In this case, Mg has to be used as a first choice therapy.
next study: does replenishing magnesium work?
http://onlinelibrary.wiley.com/doi/10.1 ... x/abstract
The effect of magnesium oral therapy on spasticity in a patient with multiple sclerosis
The effects of magnesium glycerophosphate oral therapy on spasticity was studied in a 35-year-old woman with severe spastic paraplegia resulting from multiple sclerosis (MS). We found a significant improvement in the spasticity after only 1 week from the onset of the treatment on the modified Ashworth scale, an improvement in the range of motion and in the measures of angles at resting position in lower limbs. No side-effects were reported and there was no weakness in the arms during the treatment.
active members shape site content. if there is a problem, speak up!
use the report button to flag problematic post content to volunteer moderators' attention.
i'm off to heat & eat a slice of magnesium pie (spinach, dill, parsley and green onions w feta in phyllo) 
[/quote]
