Gilenya, may increase risk of macular edema in some patients
Gilenya, may increase risk of macular edema in some patients
The first U.S. Food and Drug Administration-approved oral medication for multiple sclerosis poses a potential risk of macular edema, particularly in patients with a history of uveitis, according to a neuro-ophthalmologist.
MS patients who receive Gilenya (fingolimod, Novartis) should undergo baseline and follow-up examinations 3 to 4 months after initiation of treatment, Robert C. Sergott, MD, said at the Wills Eye Institute Alumni Conference in Philadelphia.
“The macular edema issue is one that we as ophthalmologists are very familiar with and most neurologists are not familiar with,” he said. “It’s our obligation then to help them take care of these patients because we have an intersection of MS with a medication that can cause visual loss.”... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1309
MS-UK - http://www.ms-uk.org/
- euphoniaa
- Volunteer Moderator
- Posts: 798
- Joined: Sat Jul 15, 2006 2:00 pm
- Location: midwest U.S.
- Contact:
Re: Gilenya, may increase risk of macular edema in some pati
Yeah, my history of macular edema is one of the (many) reasons I'm going to have to decline my neuro's latest suggestion that I take Gilenya. My background also hits a few of the other main Warnings and Precautions listed in the prescribing information for Gilenya, which my neuro didn't notice.squiffy2 wrote:
The first U.S. Food and Drug Administration-approved oral medication for multiple sclerosis poses a potential risk of macular edema, particularly in patients with a history of uveitis, according to a neuro-ophthalmologist.
MS patients who receive Gilenya (fingolimod, Novartis) should undergo baseline and follow-up examinations 3 to 4 months after initiation of treatment, Robert C. Sergott, MD, said at the Wills Eye Institute Alumni Conference in Philadelphia.
“The macular edema issue is one that we as ophthalmologists are very familiar with and most neurologists are not familiar with,” he said. “It’s our obligation then to help them take care of these patients because we have an intersection of MS with a medication that can cause visual loss.”... Read More - http://www.msrc.co.uk/index.cfm/fuseact ... ageid/1309
From the drug info -
The Warnings and Precautions list 7 items including –
1. Cardiac Disorders (I have a family history of heart attacks.)
2. Macular Edema (I have a personal history of ME.)
3. Increase in blood pressure ( I have poorly controlled HBP.)
Drug Interactions: I take 1 of them – a beta blocker (I was taking 2 of the meds in the precautions at the time she suggested Gilenya, but just dropped the 2nd one. )
Dx'd with MS & HNPP (hereditary peripheral neuropathy) 7/03 but must have had MS for 30 yrs before that. I've never taken meds for MS except 1 yr experiment on LDN. (I found diet, exercise, sleep, humor, music help me the most.)
-
- Similar Topics
- Replies
- Views
- Last post
-
- 1 Replies
- 7720 Views
-
Last post by ElliotB
-
- 0 Replies
- 2984 Views
-
Last post by NHE
-
- 0 Replies
- 797 Views
-
Last post by NHE
-
- 6 Replies
- 9310 Views
-
Last post by ElliotB
-
- 0 Replies
- 2775 Views
-
Last post by NHE
-
- 0 Replies
- 4495 Views
-
Last post by NHE
-
- 0 Replies
- 1715 Views
-
Last post by NHE
-
- 0 Replies
- 1945 Views
-
Last post by NHE
-
- 11 Replies
- 3804 Views
-
Last post by NHE