Anyone tried Citicoline (CDP-Choline)

[Frank]

Its available as a supplement and has neuroprotective and neurotrophic properties and is widely uses for ischemic stroke in Europe. It is said (after encouraging preliminary results there is a phase-III trial running now) that stroke patients treated with Citicoline have a better outcome regarding sustained disability.

In terms of MS I only found a patent from 2004 that combines Citicoline with steroids, but no published data on MS.

Has anyone tried it for MS? Any thoughts on that drug?

--Frank

[ikulo]

Just wanted to bump this to see if anyone has had any experience with this yet.

[NHE]

I have no experience with citicoline. However, here's a freely available review paper on it (although it is a few years old now).

http://ntp.neuroscience.wisc.edu/facult ... atla80.pdf

The paper's abstract states that citicoline is thought to increase the biosynthesis of phosphatidylcholine.

NHE

[NHE]

Here are some additional papers from the same author.

CDP-choline Significantly Restores Phosphatidylcholine Levels by Differentially Affecting Phospholipase A2 and CTP: Phosphocholine Cytidylyltransferase after Stroke
http://ntp.neuroscience.wisc.edu/facult ... tla281.pdf

Cytidine 5 0 -Diphosphocholine (CDP-Choline)in Stroke and Other CNS Disorders.
http://ntp.neuroscience.wisc.edu/facult ... atla30.pdf

More papers from this author are available from the following link.
http://ntp.neuroscience.wisc.edu/faculty/adibhatla.html


NHE

[ikulo]

Thanks for the info, NHE! Will check that out.