The trace of MS in the brain was disappeared?

[themiller]

Hi,

I have MS disease for the last 14+ years. I recently visited an MS clinic and they claimed that they could not see any trace of MS disease in the MR results (of my brain). Is it possible? Can the traces of MS in my brain disappear? Or should I be worried about the first diagnosis that is made 14 years ago?

[FLJhawk]

Do you still have symptoms of MS? Did you ever have symptoms of MS???

[HarryZ]

Hi,

I have MS disease for the last 14+ years. I recently visited an MS clinic and they claimed that they could not see any trace of MS disease in the MR results (of my brain). Is it possible? Can the traces of MS in my brain disappear? Or should I be worried about the first diagnosis that is made 14 years ago?

In the past few years researchers are saying that the lesions found in the brain's grey matter has a far more effect on one's MS than any lesions found in the white matter. We also know that lesions in white matter can come and go on their own and really aren't an accurate measure of one's MS. Add to the fact that almost all MRIs of MS patients' brains are done of the white matter makes diagnosing and following the disease far more difficult than ever.

Harry

[offaduxback]

So Harry they yet again are changing the rules to fit their own criteria. The current method of diagnosis goes back to a theory in the 19th century upon autopsy, this method doesnt seem to have ever been questioned for some reason.

How do they know that whiplash or trauma doesnt cause this kind of influence to the brain thus causing a false impression.

Are the saying that the diagnostic tool that they have been using for years up until now is the incorrect one

[HarryZ]

So Harry they yet again are changing the rules to fit their own criteria. The current method of diagnosis goes back to a theory in the 19th century upon autopsy, this method doesnt seem to have ever been questioned for some reason.

How do they know that whiplash or trauma doesnt cause this kind of influence to the brain thus causing a false impression.

Are the saying that the diagnostic tool that they have been using for years up until now is the incorrect one

The number of lesions found in a MS patient's white matter has been one criteria for many years in helping diagnose MS. But notice I say "helping diagnose" MS. The docs normally don't base a final diagnosis on MRI lesions alone.

The drug companies, in their trials, have used the number of MS lesions in white matter MRIs as their measurement that the the particular drug is working...or not. Yet there is little correlation between lesions and MS symptoms. But hey, if it helps a drug get approved and brings in millions of dollars of revenue...why not?

Now they have machines that can measure grey matter lesions which appear to be a far more accurate in determining the level of MS one has.

Changing the criteria to suite the diagnosis...who knows but I would have far more reliance on grey matter lesions than anything in the past.

Harry