George HSCT risk factors

[RyanYum]

I was just wondering what your thoughts were on risk factors after hsct such as

When looking to all-cause mortality in a cohort of almost 1500 patients who survived 2 or more years after allo-HSCT, mortality rates remain twice as high as that of the general population among 15-year survivors of allo-HSCT, and that the survivors face challenges affecting their health and well-being. Relapse of primary disease (29%) and chronic GVHD (cGVHD; 22%) were the leading causes of premature death.3 Moreover, in patients who have survived for at least 5 years after allo-HSCT without recurrence of the original disease, life expectancy is still not fully restored. Mortality rates remained four- to ninefold higher than those expected in the general population for at least 30 years after transplantation, providing an estimated 30% lower life expectancy, regardless of current age.

How do you feel the risks measured up with the reward.

[Pesho]

Hi, can you provide this study that you are citing? And I believe you are talking not only for MS patients, but mainly for cancer treatment and I think the protocols are different. Also what is the life expectancy without the treatment and on crab drugs?

[iKat]

Is this is HSTC where the rate of mortality is increased in MS patients after the treatment??