CCSVI and CCVBP

[uprightdoc]

It is often difficult to tell the difference between inflammation and edema on brain scans and inflammation is only one aspect of traumatic brain injuries. There are other aspects such as gliosis, hypoperfusion, chronic ischemia, edema and ectopia to name a few. TBI can also cause craniocervical syndromes and faulty craniospinal hydrodynamics that can lead to destructive pressure waves and hydrocephalus. The same is true for spinal cord injuries. Injuries to the spinal cord are similarly often associated with traumatic injuries of the spine. Traumatic injuries of the lower spine can lead to spondylosis and stenosis which can cause faulty craniospinal hydrodynamics. Faulty craniospinal hydrodynamics can in turn lead to chronic ischemia, edema and hydrocephalus.

[Rogan]

Uprightdoc,

I wanted to give you an update and ask a question.

I went to a very informative talk given by the Michael J Fox Foundation. They have spent 450 million trying to cure Parkinson's. I had noted on this forum before that you and Dr. Scott Rosa asked for a grant from them to use the Fonar Upright MRI to confirm your theory that Skull/Spinal Column compression leads to fluid flow disturbance and plays a roll in Parkinson's.

I believe you also believed that this minor compression might not be noticeable when lying down on an MRI hence your grant proposal.

At the meeting, which was mostly about the drugs, bio-markers, and genetic work their foundation is funding, I asked them if they had funded your grant. They were not sure.

I was able to explain your theory to one of the speakers and gave her my final copy of your book (Time for me to buy some more), she said she would pass it on to one of their PHD's and I asked that they read the chapter on Parkinson's. I also gave her Dr. Scott Rosa's name. They were dismissive at first to thinking that an MRI could help this problem, but as I described your theory no-one was really able to blow a hole in it.

Anyhow, did their foundation fund your project? Or did someone else?

Also, am I correct in describing what you and Dr. Rosa had proposed for a project. To me this sounds like a very cheap/simple theory to test out?

Thanks for all of your help....for anyone reading this not familiar with the UprightDoc's theory here's the link...

http://www.upright-health.com/parkinsons.html

[uprightdoc]

Hello Rogan,

I mention the Fox Foundation in my book. I first contacted them years before I met Dr. Rosa and never even got a reply. As I predicted in my book it turned into just another celebrity based promotional organization for the pharmaceutical industry and federal grant industry. As far as I know the proposal to investigate a connection between PD and faulty craniospinal hydrodynamics caused by craniocervical syndromes was not accepted. I cover Parkinson's and the Parkinson's Plus conditions such as olivopontocerebellar atrophy, multisystem atrophy and progressive supranuclear palsy in my next paper. Primary Parkinson's affects the substania nigra, which is part of the midbrain. The midbrain is surrounded by the quadrigeminal and interpeduncular cisterns that are filled with CSF. The midbrain is also penetrated by the cerebral aqueduct which connects the the third and fourth ventricle. Because it is penetrated by the aqueduct and surrounded by cisterns the midbrain is particularly vulnerable to faulty craniospinal hydrodynamics. Many important nerve centers are located close to the cerebral aqueduct such as those that control eye conjugation (coordination). Among other things, I suspect that faulty craniospinal hydrodynamics may play a role in diplopia and nystagmus seen in progressive supra nuclear palsy (PD Plus)and MS. One of the current primary suspects in faulty craniospinal hydrodynamics is venous insufficiency. The primary drainage system for the brain during upright posture is the accessory/emissary venous system that passes through the craniocervical junction (upper cervical spine) and drains into the vertebral venous plexus. Malformations and misalignments of the cranioscervical junction can cause obstruction of blood and CSF flow through the craniocervical junction resulting in faulty craniospinal hydrodynamics. Faulty craniospinal hydrodynamics can in turn lead to chronic ischemia, edema and hydrocephalus. It can also cause destructive increased pressure waves (B-waves) in the brain.

[lyndacarol]

Hello Rogan,

I mention the Fox Foundation in my book. I first contacted them years before I met Dr. Rosa and never even got a reply. As I predicted in my book it turned into just another celebrity based promotional organization for the pharmaceutical industry and federal grant industry. As far as I know the proposal to investigate a connection between PD and faulty craniospinal hydrodynamics caused by craniocervical syndromes was not accepted. I cover Parkinson's and the Parkinson's Plus conditions such as olivopontocerebellar atrophy, multisystem atrophy and progressive supranuclear palsy in my next paper. Primary Parkinson's affects the substania nigra, which is part of the midbrain. The midbrain is surrounded by the quadrigeminal and interpeduncular cisterns that are filled with CSF. The midbrain is also penetrated by the cerebral aqueduct which connects the the third and fourth ventricle. Because it is penetrated by the aqueduct and surrounded by cisterns the midbrain is particularly vulnerable to faulty craniospinal hydrodynamics. Many important nerve centers are located close to the cerebral aqueduct such as those that control eye conjugation (coordination). Among other things, I suspect that faulty craniospinal hydrodynamics may play a role in diplopia and nystagmus seen in progressive supra nuclear palsy (PD Plus)and MS. One of the current primary suspects in faulty craniospinal hydrodynamics is venous insufficiency. The primary drainage system for the brain during upright posture is the accessory/emissary venous system that passes through the craniocervical junction (upper cervical spine) and drains into the vertebral venous plexus. Malformations and misalignments of the cranioscervical junction can cause obstruction of blood and CSF flow through the craniocervical junction resulting in faulty craniospinal hydrodynamics. Faulty craniospinal hydrodynamics can in turn lead to chronic ischemia, edema and hydrocephalus. It can also cause destructive increased pressure waves (B-waves) in the brain.

This is now the second time I have seen/heard of these conditions.
The first time was in the following video:



Diagnosing and Treating Vitamin B12 Deficiency

@19:12 Screen statement says, RED FLAG: Multiple System Atrophy
@19:21 Friend, Dr. Harvey Barnett, and on-screen mention of Olivo-ponto-cerebellar Atrophy

[Rogan]

Uprightdoc,

That's too bad they didn't take you or Dr. Rosa up on this study.

Do you have any idea what the cost would be?

I could contact the Michael J Fox Foundation and see if I could raise the money to support your grant. I would raise their 10% or 20% admin also.

I do think there are good people at that Foundation, it's just that the entire medical system is structured around making money. There's money in drugs, so there are more people in that field.

It is odd that here is a chance to look for the root cause and they are more interested in developing a vaccine that would kill your cells that are trying to clean up the dead protein deposits found in a Parkinson's brain.

The economic incentives in medicine right now are bizarre.

If you could convince someone that you could patent a neck collar, or stent, or device that would help people. Folks would throw money at you. As far as I know a treatment can't be patented and protected. So business just ignores this.

[uprightdoc]

Rogan,

I don't know what the cost would be but it would be based on upright and cine MRI.

There have been some very promising interesting recent developments regarding Parkinson's and olivopontoncerebellar atrophy I will be covering in my next paper.

[uprightdoc]

... I could contact the Michael J Fox Foundation and see if I could raise the money to support your grant. I would raise their 10% or 20% admin also...

A better idea would be to skip the intermediary medical expert skeptics and have Michael Fox contact me directly by phone or email. I have always been interested in his case because he played hockey and was knocked unconscious once if not twice as I recall from a hard check against the sideboards. I would be happy to explain the connection between craniocervical trauma, craniocervical syndromes, craniospinal hydrodynamics and neurodegenerative diseases to him. Moreover, the research I am proposing has far greater implications than Parkinson's alone. It also includes Parkinson's Plus syndromes mentioned previously, Alzheimer's, MS and ALS, as well as other conditions.

[uprightdoc]

Here is another foundation that was founded and funded by a celebrity for supporting research into progressive supranuclear palsy. I contacted them about five years ago. They never got back to me. It's unfortunate because we are getting close to solving the puzzle.

The Richard Rainwater and Michael Fox foundations could be a big help and give a significant boost to this research if they could just get past the current medical gatekeepers and listen. I suspect that Michael Fox is a classic case of traumatic craniocervical syndrome causing faulty craniospinal hydrodynamics and neurodegenerative conditions. There are also many other celebrities in contact sports who need to get on board such as those in football, soccer (football) and boxing.

http://www.star-telegram.com/news/local ... 94849.html

http://www.rainwatercharitablefoundatio ... l-research

[Rogan]

Uprightdoc,

Yes, that is actually what I asked the speakers from the Michael J Fox Foundation, that your proposal I believed was to scan Michael in a Fonar Upright MRI.

They quickly responded that that will never happen.

I can imagine they may get requests from time to time to examine or work on Michael and I could understand their reluctance to just say ok to someone regarding that, even though I believe an MRI is harmless.

This Rainwater Foundation sounds like a perfect fit for you.

They also are concentrating on Tau. I can't believe that every researcher out there thinks that degenerative brain disease is the same as some sort of infectious disease. Like these folks caught something that causes the brain cells to just transform into useless different proteins. Then they want to treat it that way. Or they think that it is some sort of genetic disease. I imagine they believe football players all "catch" chronic traumatic encephalopathy from each other.

Common sense tells us that both the infection and genetic vectors are BS. One can't catch Parkinson's from another with it. Families don't have Parkinson's running in them like common genetic conditions.

It is clearly a degenerative cell disease that has some root cause. SOMETHING IS CAUSING THE DEGENERATION
It also blows my mind that doctors dismiss abnormal fluid flow as a possible cause. Fluid flow plays a role in so many deadly diseases and is a component to every disease/organ there is. With a brain consuming 25% of our fluid, fluid should mathematically play an even large role in brain disease.

The only thing that will clear up this ill informed thinking is going to be you figuring out a cure and curing folks like Zamboni. After that Survivor Bias will change the future.

Let me know if there's a way to help you and Dr. Rosa fund an examination of these folks. Have you scanned Parkinson patients in a Fonar yet?

[Rogan]

Sorry Uprightdoc,

I guess one of my questions has already been answered:

http://www.fonar.com/news/052114.htm

That is great people are getting help!!!

Is this therapy helping folks with Parkinson's?

[uprightdoc]

No problem Rogan.

What was the question for which you found an answer?

Specific upper cervical can be helpful for certain cases of Parkinson's, as well as other neurodegenerative conditions. There are other manual and surgical methods of correction that need to be studied as well.

[NZer1]

Rogan I think your clarity is great and I would like to add that there are examples in all camps of searching for clues to what has caused or more importantly influenced diseases to occur.

I find that there are people who have key similarities with their assessments of causes for symptoms and disease. But the most important factor is that we are not all having the same group of influences to 'cause' health issues.

To word this another way there are diseases which are called mimics or diseases that share symptoms and diseases that share clinical observations. This is the important detail that helps to show that there are sets of issues for health problems at the level of, for instance, MS. One thing is not the sole cause, many things need to occur for a cascade concept to occur over time.

So saying that pathogens are not a key factor is a dream, imo.

Or to say that inflammation is simplistic in its cause.

Or to say that progression of a disease is a single cause or factor.

Or to say infections couldn't be a factor when very little is understood of bacteria and their abilities to mutate and live in bio-films so they can share DNA with other bacteria and so on.

Or to say that diet isn't a factor in the disease commencing or in later stages improving health.

I believe that we have to be open minded about what each PwMS has as 'their disease'.

Regards,
Nigel

[NZer1]

It would be interesting to have direct access to Michael Fox and be able to talk through why an Upright MRI would be a challenge?

Could finding a 'cause' potential insight be an issue?

Rocking the Boat of the Medical World is a risk?

[Rogan]

Uprightdoc,

One question answered was the success in using the upright MRI to evaluate and treat a high profile patient. Wish I had asked the Fox foundation to join the NFL and Jim McMahon in the future.

[uprightdoc]

I think that I could get Michael Fox to support the research if I could explain it to him. Most laypeople with common sense get it. Unfortunately, I don't think Michael makes the decisions about which projects to support.