"Who would/could do such a study?" In my opinion,
many could; but
too few are!
Rehabilitation with neuromuscular electrical stimulation leads to functional gains in ambulation in patients with secondary progressive primary progressive multiple sclerosis: a case series report. (2010)
TL Wahls, D Reese, D Kaplan, WG Darling
http://www.ncbi.nlm.nih.gov/pubmed/21138391
Conclusions: NMES [neuromuscular electrical stimulation], an approved Food and Drug Administration treatment modality for muscle spasm, muscle pain, and disuse atrophy – all of which are commonly in patients with gait disability associated with SPMS and PPMS – was associated with measurable gains in ambulatory function. Additional studies are warranted.
A multimodal intervention for patients with secondary progressive multiple sclerosis: feasibility and effect on fatigue. (2014)
B Bisht, WG Darling, RE Grossmann, ET Shivapour, SK Lutgendorf, LG Snetselaar, MJ Hall, MW Zimmerman, TL Wahls
https://www.ncbi.nlm.nih.gov/pubmed/24476345
Conclusions: In this small, uncontrolled pilot study, there was a significant improvement in fatigue in those who completed the study. Given the small sample size and completer rate, further evaluation of this multimodal therapy is warranted.
Neuromuscular electrical stimulation for skeletal muscle function. (2012)
BM Doucet, A Lam, L Griffin
http://www.ncbi.nlm.nih.gov/pubmed/22737049
Different methods of applying electrical current to modify neuromuscular activity are electrical stimulation (ES), neuromuscular electrical stimulation (NMES), transcutaneous electrical nerve stimulation (TENS), and functional electrical stimulation (FES). This review covers the aspects of electrical stimulation used for rehabilitation and functional purposes. Discussed are the various parameters of electrical stimulation, including frequency, pulse width/duration, duty cycle, intensity/amplitude, ramp time, pulse pattern, program duration, program frequency, and muscle group activated, and how they affect fatigue in the stimulated muscle.