Any help and advice appreciated

[Nivek83]

Hi i am looking for any help and advice anybody can give me . In 2013 i was diagnosed with PoTS (Postural Orthostatic Tachycardia Syndrome) after suffering numerous blackouts and having a tilt table test which confirmed PoTS. I was given Midodrine to raise my blood pressure , told to increase my salt and water intake and had a pacemaker implanted to stop 6 second pauses of my heart at night, despite these i continued having so many symptoms including excessive sweating , nausea, brain fog , tremors , occipital headaches, temperature regulation problems , weakness, numbness and difficulty sleeping. I was eventually sent to neurology just to see if anything else was happening . The neurologist did a long examination and found i had positive bilateral hoffman's sign, decreased pinprick sensation on entirety of right arm, Crossed adductors , hyperreflexia and pectoralis . The neurologist then arranged a MRI for my brain which was normal but the neurologist then recently sent me for a MRI Cervical Neck based on my symptoms and occipital headaches and nerve conduction test on my right arm. I have yet to receive any results and i'm nervously waiting so i tried looking up the neurologists findings online which confused me even more so if someone could explain to me what they mean i would appreciate and where do i go next if the MRI shows nothing again , or what happens if it does, sorry i'm just messed up now.

[jimmylegs]

heya
i just threw POTS and deficiency in google and the top result is about POTS and b12 deficiency in adolescence.
https://www.ncbi.nlm.nih.gov/pubmed/24366986
"We defined vitamin B12 deficiency as a serum level <300 pg/mL.(1-4) RESULTS: Vitamin B12 levels were significantly lower in the patient group compared with the control group (47.2% vs 18%, P < .001). In the patient group, children with the POTS pattern had significantly lower vitamin B12 levels compared with children without the POTS response (P = .03)."

wiser to use 500 pg/ml as a lower cutoff. i've had undetectable b12 before, and have been using 500 pmol/L (which is more like 677 pg/ml) for about a decade. seems to be keeping things on an even keel.
that said, i have never had a POTS dx so.
for you, might be something to check in on. do you have a serum cobalamin result on file?

this is also showing up:
Postural orthostatic tachycardia syndrome is associated with platelet storage pool deficiency.
https://www.ncbi.nlm.nih.gov/pubmed/27631244
which will make me search out what deficiencies might be associated with platelet storage pool deficiency lol

also seeing links to anxiety/panic, is that in the picture for you personally?

[Nivek83]

I do have anxiety and depression treated by Fluoxetine and Psychology , as for the deficiency and serum cobalamin you mentioned i have no idea sorry, i don't think i've ever had any those test on my record. I do have Vitamin D deficiency though which i'm on 20,000 Units of Colecalciferol.

[jimmylegs]

ok re anxiety and depression, do you have a serum magnesium result on file? researchers use magnesium deficiency to test antidepressant drugs. could be an idea to see if you can rule magnesium issues out as a factor in your own case. oddly, as i check on poss nutrient depletion side effects for fluoxetine, magnesium is there. it's just a claim on a site though - am looking for an actual study which has found this effect. no luck so far. i really wouldn't like to think the drug that is treating a condition, is also perpetuating its necessity. sounds like percs withdrawal.

re cobalamin, can you share info on your diet? for example typical breakfasts lunches and dinners, how they vary weekdays and weekends? as specific as possible if you can.

re 20K of cholecalciferol. how long have you been doing that, is that daily or weekly, and do you take it on its own, or with any cofactors?