Vitamin D receptor gene is altered in MS

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We all know the relationship between low vitamin D and sunshine and MS. There is also a genetic relationship. This article shows that Vitamin D receptors (VDR) are altered in MS patients:

Vitamin D receptor gene is epigenetically altered and transcriptionally up-regulated in multiple sclerosis
http://journals.plos.org/plosone/articl ... ne.0174726

Conclusions

An alternative promoter of the VDR gene shows altered DNA methylation levels in patients with multiple sclerosis, and it is associated with VDR mRNA upregulation. This locus may represent a candidate regulatory element in the genome relevant to MS pathogenesis.