Air pollution
Re: Air pollution
2024 Jul 4
Associations of ambient air pollution exposure and lifestyle factors with incident dementia in the elderly: A prospective study in the UK Biobank
https://pubmed.ncbi.nlm.nih.gov/38972114/
Conclusion: The increased exposures of NO2, NOX, or PM2.5 are associated with elevated risk of dementia among elderly UK Biobank population. These air pollutants take joint effects with low PA, poor sleep patterns, and smoking on the development of dementia. In addition, moderate to high levels of PA could attenuate the incident risk of AD caused by air pollution. Further prospective researches among other cohort populations are warranted to validate these findings.
Associations of ambient air pollution exposure and lifestyle factors with incident dementia in the elderly: A prospective study in the UK Biobank
https://pubmed.ncbi.nlm.nih.gov/38972114/
Conclusion: The increased exposures of NO2, NOX, or PM2.5 are associated with elevated risk of dementia among elderly UK Biobank population. These air pollutants take joint effects with low PA, poor sleep patterns, and smoking on the development of dementia. In addition, moderate to high levels of PA could attenuate the incident risk of AD caused by air pollution. Further prospective researches among other cohort populations are warranted to validate these findings.
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Re: Air pollution
2024 Jul 13
Center of Health Administration and Development Studies, School of Public Health, Hubei University of Medicine, China
Assessing long-term effects of gaseous air pollution exposure on mortality in the United States using a variant of difference-in-differences analysis
https://pubmed.ncbi.nlm.nih.gov/39003417/
..This nationwide DID analysis provided causal evidence for independent and combined effects of NO2, CO, SO2, and O3 on increased mortality risks among the US general population.
Center of Health Administration and Development Studies, School of Public Health, Hubei University of Medicine, China
Assessing long-term effects of gaseous air pollution exposure on mortality in the United States using a variant of difference-in-differences analysis
https://pubmed.ncbi.nlm.nih.gov/39003417/
..This nationwide DID analysis provided causal evidence for independent and combined effects of NO2, CO, SO2, and O3 on increased mortality risks among the US general population.
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Re: Air pollution
2024 Nov 15
Association between prenatal air pollutant exposure and autism spectrum disorders in young children: A matched case-control study in Canada
https://pubmed.ncbi.nlm.nih.gov/39084506/
..Exposure to NO2 before and during pregnancy was significantly associated with ASD in offspring.
Association between prenatal air pollutant exposure and autism spectrum disorders in young children: A matched case-control study in Canada
https://pubmed.ncbi.nlm.nih.gov/39084506/
..Exposure to NO2 before and during pregnancy was significantly associated with ASD in offspring.
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Re: Air pollution
2024 Aug 9
Key Laboratory of Environment and Health, Ministry of Education, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Air pollutants, genetic susceptibility and the risk of schizophrenia: large prospective study
https://pubmed.ncbi.nlm.nih.gov/39117363/
Conclusions: Long-term exposure to air pollutants was positively related to the schizophrenia risk. Furthermore, high genetic susceptibility could increase the effect of NO2 and NOx on schizophrenia
Key Laboratory of Environment and Health, Ministry of Education, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Air pollutants, genetic susceptibility and the risk of schizophrenia: large prospective study
https://pubmed.ncbi.nlm.nih.gov/39117363/
Conclusions: Long-term exposure to air pollutants was positively related to the schizophrenia risk. Furthermore, high genetic susceptibility could increase the effect of NO2 and NOx on schizophrenia
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Re: Air pollution
2024 SepPetr75 wrote: ↑Sat Jun 22, 2024 10:29 am Coronavirus and Air Pollution
hsph.harvard.edu
https://www.hsph.harvard.edu/c-change/s ... pollution/
While the study does not show that air pollution directly affects an individual’s likelihood of dying from COVID-19 because individual-level COVID data is not yet publicly available, it does show an association between long term exposure to air pollution and higher COVID-19 mortality rates.
Air Pollution in Relation to COVID-19 Morbidity and Mortality: A Large Population-Based Cohort Study in Catalonia, Spain (COVAIR-CAT)
https://pubmed.ncbi.nlm.nih.gov/39468856/
Conclusions: Linkage across several registries allowed the construction of a large population-based cohort, tracking COVID-19 cases from primary care and testing data to hospital admissions, and death. Long- and short-term exposure to ambient air pollution were positively associated with severe COVID-19 events. The effects of long-term air pollution exposure on COVID-19 severity were greater among those with lower individual- and area-level SES.
area-level socioeconomic status (SES)
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Re: Air pollution
2024 Nov 23
Association between air pollution and hypertension hospitalizations: a time series analysis in Lanzhou
https://pubmed.ncbi.nlm.nih.gov/39580430/
Results: A total of 47,884 cases of hypertension hospitalizations were included. Short-term exposure to NO2 and CO increased the risk of hypertension hospitalization. For each 10 µg/m3 increase in NO2 and each 1 mg/m3 increase in CO, the relative risk (RR) for hypertension hospitalization were highest at lag0-3 (RR: 1.0427; 95% CI: 1.0196, 1.0663) and lag3 (RR: 1.0986; 95% CI: 1.0350, 1.1661), respectively. SO2 at different lag structures showed opposite effects on hypertension hospitalization. O3 was significantly negatively associated with hypertension hospitalization. No correlation was observed between PM2.5 and PM10 and hypertension hospitalization. Females and individuals aged ≥ 65 were more susceptible to air pollution. The harmful effects of air pollution are greater in the cold season.
Association between air pollution and hypertension hospitalizations: a time series analysis in Lanzhou
https://pubmed.ncbi.nlm.nih.gov/39580430/
Results: A total of 47,884 cases of hypertension hospitalizations were included. Short-term exposure to NO2 and CO increased the risk of hypertension hospitalization. For each 10 µg/m3 increase in NO2 and each 1 mg/m3 increase in CO, the relative risk (RR) for hypertension hospitalization were highest at lag0-3 (RR: 1.0427; 95% CI: 1.0196, 1.0663) and lag3 (RR: 1.0986; 95% CI: 1.0350, 1.1661), respectively. SO2 at different lag structures showed opposite effects on hypertension hospitalization. O3 was significantly negatively associated with hypertension hospitalization. No correlation was observed between PM2.5 and PM10 and hypertension hospitalization. Females and individuals aged ≥ 65 were more susceptible to air pollution. The harmful effects of air pollution are greater in the cold season.
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Re: Air pollution
2024 Nov 25
Impact of ambient air pollution on hospital visits for mental and behavioral disorders among residents in an industrial area in Henan Province from 2016 to 2021
https://pubmed.ncbi.nlm.nih.gov/39607002/
Conclusion: Exposure to air pollution can increase hospital visits for mental and behavioral disorders among residents in industrial areas, with a higher risk among those aged<45 years old and during the cold season.
Impact of ambient air pollution on hospital visits for mental and behavioral disorders among residents in an industrial area in Henan Province from 2016 to 2021
https://pubmed.ncbi.nlm.nih.gov/39607002/
Conclusion: Exposure to air pollution can increase hospital visits for mental and behavioral disorders among residents in industrial areas, with a higher risk among those aged<45 years old and during the cold season.
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Re: Air pollution
2024 Dec 9
Air pollution is associated with increased risk of venous thromboembolism: the Multi-Ethnic Study of Atherosclerosis
https://pubmed.ncbi.nlm.nih.gov/39652776/
..O3 was not related. In this prospective community-based cohort with individual-level estimation of chronic air pollution exposure, higher average ambient concentrations of PM2.5, NO2 and NOX were associated with greater risk of developing VTE.
Air pollution is associated with increased risk of venous thromboembolism: the Multi-Ethnic Study of Atherosclerosis
https://pubmed.ncbi.nlm.nih.gov/39652776/
..O3 was not related. In this prospective community-based cohort with individual-level estimation of chronic air pollution exposure, higher average ambient concentrations of PM2.5, NO2 and NOX were associated with greater risk of developing VTE.
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Re: Air pollution
2024 Dec 18
Mental health center and laboratory of psychiatry, West China Hospital, Sichuan University, Chengdu, China
Linking ambient air pollution to mental health: evidence based on the two-sample Mendelian randomization and colocalization study
https://pubmed.ncbi.nlm.nih.gov/39695075/
... Our findings support causal associations between exposure to ambient air pollution, particularly PM2.5, NO2, and NOx, and an increased risk of specific mental disorders.
Mental health center and laboratory of psychiatry, West China Hospital, Sichuan University, Chengdu, China
Linking ambient air pollution to mental health: evidence based on the two-sample Mendelian randomization and colocalization study
https://pubmed.ncbi.nlm.nih.gov/39695075/
... Our findings support causal associations between exposure to ambient air pollution, particularly PM2.5, NO2, and NOx, and an increased risk of specific mental disorders.
https://www.eboro.cz
Re: Air pollution
2024 Dec 18
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York
Impact of Endocrine-Disrupting Chemicals, Climate, and Air Pollution on Pregnancy Outcomes: A Scoping Review
https://pubmed.ncbi.nlm.nih.gov/39694048/
..Air pollution, notably PM2.5, NO2, and O3, has been linked to increased rates of preterm birth, low birth weight, and stillbirth.
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York
Impact of Endocrine-Disrupting Chemicals, Climate, and Air Pollution on Pregnancy Outcomes: A Scoping Review
https://pubmed.ncbi.nlm.nih.gov/39694048/
..Air pollution, notably PM2.5, NO2, and O3, has been linked to increased rates of preterm birth, low birth weight, and stillbirth.
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Re: Air pollution
2024 Dec 18
The impact of long-term exposure to NO2, O3, and their oxidative potential on adolescents' mental health, and the protective role of school-based greenness
https://pubmed.ncbi.nlm.nih.gov/39719755/
Abstract
Recent increases in nitrogen dioxide (NO2) and ozone (O3), two highly reactive and oxidative pollutants, have raised concerns about their potential impact on adolescent mental health...
The impact of long-term exposure to NO2, O3, and their oxidative potential on adolescents' mental health, and the protective role of school-based greenness
https://pubmed.ncbi.nlm.nih.gov/39719755/
Abstract
Recent increases in nitrogen dioxide (NO2) and ozone (O3), two highly reactive and oxidative pollutants, have raised concerns about their potential impact on adolescent mental health...
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Re: Air pollution
2024 Dec 14
The impacts of noise and air pollution on breast cancer risk in European and East Asian populations: Insights from genetic evidence
https://pubmed.ncbi.nlm.nih.gov/39675203/
Conclusions: Our study gave new evidence from a genetic standpoint underscoring that improving the environmental quality of residential areas is conducive to reducing BC risk.
The impacts of noise and air pollution on breast cancer risk in European and East Asian populations: Insights from genetic evidence
https://pubmed.ncbi.nlm.nih.gov/39675203/
Conclusions: Our study gave new evidence from a genetic standpoint underscoring that improving the environmental quality of residential areas is conducive to reducing BC risk.
https://www.eboro.cz
Re: Air pollution
2024 Dec 30
The association between ambient air pollution and the risk of incident nasopharyngeal carcinoma in Hangzhou, China
https://pubmed.ncbi.nlm.nih.gov/39738575/
..The association between NO2 and NPC was significantly positively correlated in male, female, rural areas, and elderly subgroups. In conclusion, our study's findings demonstrated that exposure to airborne SO2, NO2, and PM10 can negatively impact the risk of incident NPC.
The association between ambient air pollution and the risk of incident nasopharyngeal carcinoma in Hangzhou, China
https://pubmed.ncbi.nlm.nih.gov/39738575/
..The association between NO2 and NPC was significantly positively correlated in male, female, rural areas, and elderly subgroups. In conclusion, our study's findings demonstrated that exposure to airborne SO2, NO2, and PM10 can negatively impact the risk of incident NPC.
https://www.eboro.cz
Re: Air pollution
2025 Jan 2
Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China
Causal relationships between air pollution and common autoimmune diseases: a two-sample Mendelian randomization study
https://pubmed.ncbi.nlm.nih.gov/3974791[i]9/
Abstract
Air pollution is strongly associated with autoimmune diseases (ADs), however, the genetic causality between them remains poorly understood. Therefore, the aim of this study is to determine the relationship between common air pollutants and ADs through Mendelian randomization (MR) analysis. We conducted a MR study using aggregated data from publicly available genome-wide association studies (GWAS). Single nucleotide polymorphisms (SNPs) associated with 5 common air pollutants are used as instrumental variables. Random-effects inverse variance weighted (IVW) is used as the primary method to assess causal relationships, with results reported in terms of odds ratios (OR). In addition, we used a two-step MR to assess the mediating role of common risk factors for ADs in the effects of air pollution on ADs. Our analysis revealed causal associations between selected air pollutants and specific ADs. Exposure to nitrogen oxides was positively associated with the risk of rheumatoid arthritis (RA) (OR = 1.47,95% CI 1.01-2.14, P = 0.043), Sjogren's syndrome (SS) (OR = 2.29,95% CI 1.08-4.89, P = 0.032), and systemic lupus erythematosus (OR = 7.26,95% CI 2.25-23.40, P = 9.10E-04). Genetically predicted PM2.5 and PM10 were risk factors for ulcerative colitis (OR = 1.68,95% CI 1.05-2.68, P = 0.032) and psoriasis (OR = 1.34,95% CI 1.02-1.76, P = 0.037), respectively. Our results also suggest a negative causal relationship between PM2.5-10 and SS (OR = 0.29, 95% CI 0.10-0.90, P = 0.032). In risk factor-related mediation analyses, BMI and smoking mediated 6% (95% CI 1-10%) and 9% (95% CI 2-17%) of the effect of nitrogen oxides on RA, respectively. This study provides evidence of a causal relationship between air pollutants and specific ADs risks, suggesting that improving air pollution may be important in preventing ADs.
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Petr: Bravo!
Department of Cardiovascular Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China
Causal relationships between air pollution and common autoimmune diseases: a two-sample Mendelian randomization study
https://pubmed.ncbi.nlm.nih.gov/3974791[i]9/
Abstract
Air pollution is strongly associated with autoimmune diseases (ADs), however, the genetic causality between them remains poorly understood. Therefore, the aim of this study is to determine the relationship between common air pollutants and ADs through Mendelian randomization (MR) analysis. We conducted a MR study using aggregated data from publicly available genome-wide association studies (GWAS). Single nucleotide polymorphisms (SNPs) associated with 5 common air pollutants are used as instrumental variables. Random-effects inverse variance weighted (IVW) is used as the primary method to assess causal relationships, with results reported in terms of odds ratios (OR). In addition, we used a two-step MR to assess the mediating role of common risk factors for ADs in the effects of air pollution on ADs. Our analysis revealed causal associations between selected air pollutants and specific ADs. Exposure to nitrogen oxides was positively associated with the risk of rheumatoid arthritis (RA) (OR = 1.47,95% CI 1.01-2.14, P = 0.043), Sjogren's syndrome (SS) (OR = 2.29,95% CI 1.08-4.89, P = 0.032), and systemic lupus erythematosus (OR = 7.26,95% CI 2.25-23.40, P = 9.10E-04). Genetically predicted PM2.5 and PM10 were risk factors for ulcerative colitis (OR = 1.68,95% CI 1.05-2.68, P = 0.032) and psoriasis (OR = 1.34,95% CI 1.02-1.76, P = 0.037), respectively. Our results also suggest a negative causal relationship between PM2.5-10 and SS (OR = 0.29, 95% CI 0.10-0.90, P = 0.032). In risk factor-related mediation analyses, BMI and smoking mediated 6% (95% CI 1-10%) and 9% (95% CI 2-17%) of the effect of nitrogen oxides on RA, respectively. This study provides evidence of a causal relationship between air pollutants and specific ADs risks, suggesting that improving air pollution may be important in preventing ADs.
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Petr: Bravo!
https://www.eboro.cz