PM10

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[Petr75]

2025 Jan 25
The role of miRNAs in the associations between particulate matter and ischemic stroke: a nested case-control study
https://pubmed.ncbi.nlm.nih.gov/39870131/

Abstract

epidemiological studies have reported that atmospheric particulate matter (PM) contributes to ischemic stroke (IS). Biological studies also indicated that the pathway where PM induces IS involves several pathological processes...

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2024 Oct 30
Causal associations of ambient particulate matter 10 and Alzheimer's disease: result from a two-sample multivariable Mendelian randomization study
https://pubmed.ncbi.nlm.nih.gov/39649256/

Conclusions: Increased PM10 levels were found to be significantly related to an increased risk of AD. This study provided evidence of genetic prediction of a causal relationship between PM10 and the risk of AD, suggesting that air pollution control may have significant implications for the prevention of AD.

2024 Nov 29
Herpes Simplex Virus 1 Infection of Human Brain Organoids and Pancreatic Stem Cell-Islets Drives Organoid-Specific Transcripts Associated with Alzheimer's Disease and Autoimmune Diseases
https://pubmed.ncbi.nlm.nih.gov/39682726/

..We observed that differentially expressed genes (DEGs) in HSV-1-infected sc-islets were enriched for genes associated with several autoimmune diseases, most significantly, T1D, but also rheumatoid arthritis, psoriasis, Crohn's disease, and multiple sclerosis

2025 Jan 29
Ambient air pollution and Alzheimer's disease and other dementias: a global study between 1990 and 2019
https://pubmed.ncbi.nlm.nih.gov/39881284/

Conclusions: The burden of dementia is expected to increase globally, given the continuously expansion of the ageing population. Air pollution was found to be significantly associated with a higher burden of AD and dementia. As a persistent challenge in urban cities, air pollution demands strict regulatory control.

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2025 Jan 29
Joint exposure to multiple air pollutants and residual cardiovascular risk in hypertension
https://pubmed.ncbi.nlm.nih.gov/39884016/

Results: Over an average follow-up period of 2.24 years (SD, 1.25), 706 hypertensive patients developed cardiovascular disease. In the single-pollutant analysis, higher concentrations of PM2.5, PM2.5-10, SO2 and CO were linked to increased residual cardiovascular risk.

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2025 Jan 10
Moderate PM10 exposure increases prostate cancer: a longitudinal nationwide cohort study (2010-2020)
https://pubmed.ncbi.nlm.nih.gov/39866357/

Results: Our findings indicate that even moderate PM10 exposure is a risk factor for developing prostate cancer. Additionally, even at low levels of PM2.5, moderate PM10 exposure significantly impacts prostate cancer development, with lifestyle ha bits potentially lowering this risk.

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2024 Jul-Dec
Profile of cognitive deficits among children residing in areas with high ambient air pollution in Odisha

https://pubmed.ncbi.nlm.nih.gov/39898080/

Conclusion: Six- to eight-year-old children residing in areas with high ambient particulate pollution exhibited lower cognitive abilities, including deficits in attention, working memory, mathematical skills, vocabulary, and visual-spatial processing.

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2025 Feb 3
Air Pollution and Oral Health: An Overall Insight From Genetic Causality
https://pubmed.ncbi.nlm.nih.gov/39904706/

Conclusion: This study highlights the detrimental impact of air pollution on oral health, emphasizing the need for further research into the underlying mechanisms and interactions. These findings reinforce the importance of implementing environmental interventions to mitigate the associated risks for oral health.

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2025 Feb 4
Impact of Ambient Air Pollution on Reduced Visual Acuity Among Children and Adolescents
https://pubmed.ncbi.nlm.nih.gov/39903915/

Conclusion: Regions with more polluted air tend to have a higher prevalence of reduced VA. Exposure to PM2.5 might be an important risk factor for myopia among children and adolescents.

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2025 Feb 8
Short-term effects of ambient air pollution on influenza incidence in Chongqing, China: a time-series analysis
https://pubmed.ncbi.nlm.nih.gov/39921626/

Influenza incidence was positively associated with PM2.5, PM10, SO2, NO2 and CO, but negatively with O3..

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[Petr75]

2025 Jan 18
Department of Biochemistry, Cancer Biology, Neuroscience & Toxicology, School of Medicine, Meharry Medical College, Nashville, TN, USA
Particulate matter 2.5 (PM2.5) - associated cognitive impairment and morbidity in humans and animal models: a systematic review
https://pubmed.ncbi.nlm.nih.gov/39827081/

....Equivocal evidence was identified from pre-clinical (animal model) and human studies that PM2.5 exposure contributes to dementia, Parkinson disease, multiple sclerosis, stroke, depression, autism spectrum disorder, attention deficit hyperactivity disorder, and neurodevelopment. In addition, there was substantial evidence from human studies that PM2.5 also was associated with Alzheimer's disease, anxiety, neuropathy, and brain tumors. The role of exposome in characterizing neurobehavioral anomalies and opportunities available to leverage the neuroexposome initiative for conducting longitudinal studies is discussed.....

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Petr:
"In my opinion, a more accurate formula is: Genes + Lifestyle + O₃ + PM₂.₅ = MS, but things can always be a little different. I am a former electrician—nothing more. I repaired machines, not people. And I also built photovoltaic systems." .

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2024 Dec 13
Ambient air pollution exposure in relation to cerebral small vessel disease in Chinese population: A cranial magnetic resonance imaging-based study
https://pubmed.ncbi.nlm.nih.gov/39925481/

....These findings suggest that a positive link between air pollutants exposure and neuroimaging markers of CSVD in the Chinese population, revealing the importance of controlling environmental pollutants to protect the population against cerebral small vessel damage.

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2025 Feb 8
Population exposure evaluation and value loss analysis of PM2.5 and ozone in China
https://pubmed.ncbi.nlm.nih.gov/39923622/

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2025 Feb 8
The microbiome of Total Suspended Particles and its influence on the respiratory microbiome of healthy office workers
https://pubmed.ncbi.nlm.nih.gov/39923562/

Abstract
Air particulate matter (PM) is widely recognized for its potential to negatively affect human health, including changes in the upper respiratory microbiome. However, research on PM-associated microbiota remains limited and mostly focused on PM (e.g., PM2.5 and PM10). This study aims to characterize for the first time the microbiome of Total Suspended Particles (TSP) and investigate the correlations of indoor TSP with the human upper respiratory microbiome...

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2024 Jul 15
Causal association between air pollution and allergic rhinitis, asthma: a Mendelian randomization study
https://pubmed.ncbi.nlm.nih.gov/39076418/

Conclusion: This Mendelian randomization study establishes a causal link between PM10 exposure and asthma, suggesting that interventions to reduce air pollution may decelerate the adverse progression of asthma.

2024 Dec 19
Advancing allergic rhinitis research through phenome-wide association studies: Insights from known genetic loci
https://pubmed.ncbi.nlm.nih.gov/39807185/

Results: The PheWAS analysis indicated significant associations between asthma, eczema, nasal polyps, hypothyroidism, and AR risk variants. Additionally, potential associations were observed with ulcerative colitis, psoriasis, chalazion, pernicious anemia, glaucoma, multiple sclerosis, arthritis, prostate cancer, varicose veins of lower extremities, and heart attack.