Crazy thoughts on non-injectibles / drug delivery

CureOrBust · Post by **CureOrBust** » Thu Jul 17, 2008 4:18 am

Its been a bit of a "holly grail" to attain an oral treatment for MS, since all our current treatments involve an injection.

My understanding of the issue a number of drugs have with oral delivery is that the stomach is a highly acidic place that destroys the actual medication in many cases.

Ok, so the plan is to move away from injections, and oral delivery is not really an options (in most cases), I am wondering why we do not see any drugs using a suppository technique for delivery? I know I would prefer this over having to inject myself 1-7 times a week. I have never seen this method even considered. It feels like they get together and agree "well they can't swallow it, lets make them inject it!" and that's the only options considered.

Sure, it sounds a little paranoid, but it doesn't mean they are not after me. huh. huh.

RuSmolikova · Post by **RuSmolikova** » Thu Jul 17, 2008 12:32 pm

Why not to take snuff of it?
As far as I know, docs already work on this way...

Slumby · Post by **Slumby** » Mon Aug 04, 2008 12:49 am

Loriyas · Post by **Loriyas** » Mon Aug 04, 2008 5:21 am

I have always wondered why not a patch?
Lori

catfreak · Post by **catfreak** » Mon Aug 04, 2008 5:17 pm

A patch would probably cause skin irritation.

A pill would be wonderful.

CF

CureOrBust · Post by **CureOrBust** » Tue Aug 05, 2008 2:10 am

Loriyas wrote:I have always wondered why not a patch?

Nicotine can be delivered in a controlled manner via a patch, but from what I understand it was very difficult technology to master. i.e. expensive.

catfreak wrote:A patch would probably cause skin irritation.

And this would be bad in comparison to injection site reactions how?

catfreak wrote:A pill would be wonderful.

I understand the stomach environment to be a major hazard for medications.

RuSmolikova wrote:Why not to take snuff of it?

I would hazard a guess that the issue with "snorting" medication, is controlling the dose?

Loriyas · Post by **Loriyas** » Tue Aug 05, 2008 8:51 am

"Nicotine can be delivered in a controlled manner via a patch, but from what I understand it was very difficult technology to master. i.e. expensive. "

This may be but it's not like the injectibles are cheap! I'd try something like this over doing a daily shot!
Lori

catfreak · Post by **catfreak** » Tue Aug 05, 2008 3:48 pm

Cure,

Injecting leaves very little drug touching the top skin. A patch would irritate a larger area for a longer period. Not a pleasant thought for me.

Just my ideas, I would try a pill.

CF