Multiple sclerosis diagnosed with other auto-immunes

[cinder21]

One question that has plagued me is if CCSVI may lead to MS (if the hypothesis is correct), why do people get diagnosed with MS and other auto-immunes such as lupus, graves disease, sacoidosis. I think i could have lupus as well so where does that fit in?

[cah]

Hello Cinder,

I'm copying a text from tzootsi (from here: http://www.thisisms.com/ftopicp-84200.html#84200 ) cause it fits here as well (and is also my suggestion):

Most CCSVI proponents, including Zamboni believe that there is an immune system aspect to MS. From what I can gather, CCSVI may be the root cause of MS, but after years of iron buildup in the nervous system, the immune system goes haywire and starts attacking. The overexcited immune system may cause all kinds to things to happen like food sensitivities, etc. Rebooting the immune system would probably bring it back into some kind of balance, but my gut feeling is that CCSVI is the underlying cause.

[magoo]

Cinder, great question!
Cah, great response!
I was suffering from Fibro on top of my MS before surgery. Both have improved. I have none of the daily aching and pain of Fibro any longer. Hopefully in time this will all be scientifically explained and understood.

[cheerleader]

Dr. Eliot Frohman stated at the conference in Bologna that CCSVI research is opening up a new way of looking at autoimmune disease. He commented that all autoimmune disease might have a venous connection:
from my notes-

Dr. Frohman makes the introduction. "CCSVI is removed from how we think about MS or any other immune mediated diseases. Could other diseases we currently classify as autoimmune be related to venous disease? AI diseases share in common molecular adhesion molecules. Perhaps Crohn’s could be venous? Validating CCSVI in MS may affect the classification of other autoimmune disorders. This venous model has been overlooked.

Micrographs and histopathologies show periventricular cuffs, red cells we see in postcapillary venules. This is not a new idea. In 1863 -before Charcot.- G.E. Rindfleisch writes of venous congestion in MS.

Could the immune system go anywhere blood goes? Is this why there is an inappropriate immune response?"

Dr. Zamboni also notes that part of the collateral circulation in CCSVI involves the thyroid veins, and this might be connected to the high level of autoimmune thyroid disease found in MSers.
cheer

[cinder21]

To Cah Thankyou for your response. This ofcorse will have to be addressed thru more research

To Magoo: Think i read somewhere that fibro is slightly controversial as it seems to be closely linked with MS as Ofcorse many with fibro do go on to develop ms

To cheer: I have been thinking that this may be the case. Many auto-immunes could have vascular roots which has been overlooked.
Lets hope this breakthorough gives rise to a cascade of others.

The other question which pops up of course is why people get different combinations of auto-immunes? Maybe thats the genetic component or it depends on which parts of the vascular system is affected.