Lassman book about pathology online

[frodo]

Recently I have found a recent (Feb. 2014) book online by Hans Lassman. This author was a collaborator with Lucchinetti during the Lesion Project studies, and did also collaborate with the team that found anti-AQP4 in Neuromyelitis optica.

The reason why I want to share this book here is because it confirms some ideas that can be interested for the studies on CCSVI. The authors support the heterogeneity of MS lesions, classify them in four patterns, assign the pattern II to antibody-mediated damage, and classify pattern III to an hypoxia-induced damaged. Therefore compatible with CCSVI.

The book is freely available here,

http://books.google.es/books?hl=en&lr=& ... &q&f=false

For the CCSVI related problem, it introduces hypoxia as the culprit for type III lesions in page 24 and, in page 295 it states that "this sparing of the corpus callosum has been attributed to having a dual blood supply, which protects it from hypoxia". This sentence sounds a lot compatible with the CCSVI theory.

Appart of that, it also hypothesizes that Kir4.1 is the culprit for pattern II lesions in page 34.