Some people has noticed that at least for some lesions the damage is done from the inside to the outside, i.e. a primary neurodegenerative process triggers later the BBB breakdown and the demyelination.
A new article has found the same again, finding that lesions can be inside-out and outside-in. Unfortunately, the researchers do not clearly say in the abstract if a given patient can have both types or only one.
http://msj.sagepub.com/content/early/20 ... 7.abstract
New report about inside-out genesis
If it's on your mind and it has to do with multiple sclerosis in any way, post it here.
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