Sun exposure in teen years ‘may delay onset of MS’

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Sun exposure in teen years ‘may delay onset of MS’

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People with multiple sclerosis tend to develop it later if they had regular sun exposure as teenagers, a new study suggests -- adding to evidence linking the condition to a lack of sunlight and vitamin D... Read More - http://www.ms-uk.org/MSnews
MS-UK - http://www.ms-uk.org/
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Leonard »

they should look at my thesis MS UNRAVELLED, see posting 10 Aug on http://www.thisisms.com/forum/general-d ... 8-720.html
there they find the explanation..
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Scott1 »

Everyone should read your piece, Leo.

This study looks a bit like making the data fit the answer they want. Try it in Australia rather than on Danes and see what it says.

Regards
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Leonard »

Hi Scott,

How are you?
The annual MS conference ECTRIMS 2015 is currently held in Barcelona Spain.
There are more than 7000 delegates..

I find the program is disappointing.
There no big steps in the thinking.

It is good to know that several meetings are held en marge of ECTRIMS.
Some of these meetings involve experts from many different medical disciplines.
I have understood that my thesis will also be on the agenda. :)

It is good that side meetings are held, outside the ECTRIMS box.
It shows that the quasi monopoly of ECTRIMS will slowly be undermined because of program restrictions and orthodox thinking.

Best regards,

Leo
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Scott1 »

Hi Leo,

That's very good news. You've done a lot of work.

I'm continuing to improve. The longer I go the more I think there is a massive confusion of cause, effect and secondary effect in the MS picture. You have done a very good job in unscrambling many of the bits.

I'm looking at nitric oxide at the moment. It's a very difficult subject and of course it ties into peroxynitrite.
If you want to go mad have a look at the papers edited by Louis J Ignarro called Nitric Oxide; Biology and Pathobiology. It is typically complex but a lot will be familiar to you. Understanding this molecule will make a lot of other things make sense.
How are you going?

Regards,
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Leonard »

I am progressive, going down slowly, haven't had any real flares after the big flares on 47 years when I was diagnosed.
It is increasingly difficult to follow a very strict diet; never had big expectations from supplementations.

I am 59 now and still walking, out of house with a cane, can walk half a mile, going down slowly but steadily.
As a man (worse prognosis), 12 years after diagnosis at later age, so I guess I may not complain, it is still better than expected.
The professor neurologist who I recently saw seemed even a bit surprised that I came walking into the office and asked what I was doing...

I am getting more and more convinced that my problem with the progression is in the spinal column.
My hands are generally ok; the latest MRI from just a few monts ago showed little difference from the one of 8 years ago.

I need fast action if I don't want to end up in a wheelchair.
Pondering on that now; Rituximab intrathecal and intravenous would be an option for me.
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Scott1 »

Hi again,

Sorry to hear that. Did you try megadosing with Q10 and adding acetyl-L-carnitine? It has made an enormous difference to me, particularly with fatigue and heat tolerance. Did you try Valtrex? I can't recall.
I'm nearly 58 and last year should have really done me in but I'm never tired and the muscles are improving. There is a lot of strength in them but I need plenty of massage to offset the tightness. I'm pretty sure I have Thoracic outlet syndrome but no one pays any attention at all. Botox helped with the spasticity in the left leg because I exercised a lot but I did need cortisone in the right hip to overcome bursitis as my gait has been altered so many times in 12 months. A tiny dose of Baclofen (5mg) was enough. I'd be interested to see what different things do to you as all this seems to help me.
I'm not sure I want to be classified as a particular form of MS. A year ago half my heart stopped working, I couldn't walk, I was constantly spasming, my blood pressure was going crazy and I was cognitively impaired. I stuck to my guns and added a couple of things in for a while so now they say I have mild MS. When I was released from hospital they told me to rest and take pain killers as well as Tecfidera. I completely ignored that advice and I am very glad I did. I do hope things get better for you.

Regards
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Leonard »

Hi Scott,

Good to hear you are doing well. It seems you are going the Terry Wahls route...

You are right that there is a massive confusion of cause, effect and secondary effect in the MS picture.
Just look at the ECTRIMS 2015 program, and find the big confusion, the symptomatic inclination to look at symptoms rather than causes.
With your work on the the papers edited by Louis J Ignarro called Nitric Oxide; Biology and Pathobiology, you are so far ahead of the gang, scaring..

I am sure the huge oxidative stress is part of the problem, we know why.
This would also explains why massive use of antioxidants may start to make a difference, after some period of time..
I think Terry Wahls also had her metabolism flooded with supplements for quite a while before she started the diet.
Physical exercise is important too.

Where you go mad on the NO papers, I go mad on the relationship gut microbiota, HERV and epigenetics.
But I am sure one day we will thrive.

Best, Leo
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Re: Sun exposure in teen years ‘may delay onset of MS’

Post by Scott1 »

Hi Leo,

Not quite the Terry Wahls route. I don't think she explains herself well enough but she is going the right way.
It is all about oxidative stress, reperfusion and inflammation. It must be so attractive to researchers to repeat experiments and backfit data. I guess they have to get paid. Your interest in gut microbiota and epigenetics fits into what I'm looking at. Its just so awfully technical with so many loops and there are no absolutes because the reactions are so fast they are hard to measure.
In essence, anything that lowers oxidative stress is a good idea.
Stay well.

Regards,
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