Teri helps recovering optic nerve

[frodo]

Teriflunomide treatment is associated with optic nerve recovery in early multiple sclerosis

https://journals.sagepub.com/doi/full/1 ... 6421997372

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Beneficial properties of TRF beyond pure peripheral immunomodulation have been hypothesized before. Preclinical data already indicated beneficial properties of TRF on the central nervous system (CNS). Generally, its capability to cross the blood–brain barrier appears a prerequisite and this feature distinguishes it from injectable substances such as GLAT and IFN.11 Within the CNS, potential mechanisms of action involve promotion of oligodendrocyte function and induction of myelin formation,11 modulation of microglia function,12 and halting of axonal perturbation.13 Interestingly, its involvement in cellular metabolism also appears to underlie its anti-inflammatory effect on lymphocytes.14

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