Tropospheric ozone

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Petr75
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Re: Tropospheric ozone

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Petr75
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Re: Tropospheric ozone

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Petr75 wrote: Thu Jan 23, 2025 10:56 am
Petr75 wrote: Mon Jul 22, 2024 9:02 pm O3

January 2010
Toxicological Sciences
Oxidative Stress Caused by Ozone Exposure Induces Loss of Brain Repair in the Hippocampus of Adult Rats

https://academic.oup.com/toxsci/article ... 87/1675262

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MS


2024 Jun 7
Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain
Oxidative Stress Markers in Multiple Sclerosis
https://pubmed.ncbi.nlm.nih.gov/38927996/

Data from analyses of central nervous system autopsy material from patients diagnosed with multiple sclerosis, as well as from studies in the main experimental model of multiple sclerosis, experimental autoimmune encephalomyelitis (EAE), suggest the possibility of a role of oxidative stress as well ..

Free full text.
2025 Jan 17.
Multiphase Radical Chemical Processes Induced by Air Pollutants and the Associated Health Effects
https://pubmed.ncbi.nlm.nih.gov/39839244/

Abstract

Air pollution is increasingly recognized as a significant health risk, yet our understanding of its underlying chemical and physiological mechanisms remains incomplete. Fine particulate matter (PM2.5) and ozone (O3) interact with biomolecules in intracellular and microenvironments, such as the epithelial lining fluid (ELF), leading to the generation of reactive oxygen species (ROS). These ROS trigger cellular inflammatory responses and oxidative stress, contributing to a spectrum of diseases affecting the respiratory, cardiovascular, and central nervous systems. Extensive epidemiological and toxicological research highlights the pivotal role of ROS in air pollution-related diseases. It is crucial to comprehend the intricate chemical processes and accompanying physiological effects of ROS from air pollutants...


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2025 Jul 2
The impact of oxidative stress on symptoms associated with multiple sclerosis
https://pubmed.ncbi.nlm.nih.gov/40596531/

Abstract

Multiple sclerosis (MS) is a chronic, inflammatory and degenerative disease affecting the central nervous system, the pathophysiology of which is unknown. Oxidative stress appears to play a significant role in the initiation and the perpetuation of the inflammatory and neurodegenerative processes associated with MS...
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Petr75
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Re: Tropospheric ozone

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2025 Nov
Ozone pollution induced-yield loss of major staple crops in China and effects from COVID-19
https://pubmed.ncbi.nlm.nih.gov/40602926/

Abstract

Surface ozone (O3) pollution showed a continuous increasing trend during the recent decades in China, posing an increasing threat to food security...
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Petr75
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Re: Tropospheric ozone

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2025 Jun 30
A Systematic Approach to Mitigate Ozone Pollution in Northern Taiwan: Evidence from De-pollutant Analysis
https://pubmed.ncbi.nlm.nih.gov/40602635/

Abstract

Strict air pollution control regulations in Taiwan have led to a gradual decrease in PM2.5 and most gaseous pollutants from 2012 to 2022, except for ozone (O3)...
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Petr75
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Re: Tropospheric ozone

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2025 Jul 9
Council for Nutritional and Environmental Medicine, Mo i Rana, Norway
Ozone-induced Neurotoxicity: Mechanistic Insights and Implications for Neurodegenerative Diseases
https://pubmed.ncbi.nlm.nih.gov/40641015/

Abstract

Ozone (O3), a reactive gas produced by sunlight-driven reactions involving nitrogen oxides and volatile organic compounds, presents serious risks to both respiratory and brain health. While its harmful effects on the lungs are well established, there is increasing evidence connecting ozone exposure to cognitive decline and neurodegenerative conditions like Alzheimer's and Parkinson's diseases. Ozone induces oxidative stress and systemic inflammation, and activates microglia, with the potential to reach the brain directly through the olfactory pathway. These mechanisms play a role in key neurodegenerative processes, such as the buildup of amyloid-beta, abnormal tau phosphorylation, and mitochondrial dysfunction. Drawing from findings in both animal and human studies, this review highlights the critical need to reduce ozone exposure to safeguard brain health and alleviate the growing impact of neurological disorders.
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